FAR1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008611Biological processether lipid biosynthetic process
GO_0010025Biological processwax biosynthetic process
GO_0046474Biological processglycerophospholipid biosynthetic process
GO_0035336Biological processlong-chain fatty-acyl-CoA metabolic process
GO_0005778Cellular componentperoxisomal membrane
GO_0005777Cellular componentperoxisome
GO_0102965Molecular functionalcohol-forming long-chain fatty acyl-CoA reductase activity
GO_0016491Molecular functionoxidoreductase activity
GO_0080019Molecular functionalcohol-forming very long-chain fatty acyl-CoA reductase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameFAR1
Protein nameFatty acyl-CoA reductase 1 (EC 1.2.1.84) (Male sterility domain-containing protein 2)
Fatty acyl-CoA reductase (EC 1.2.1.84)
Fatty acyl-CoA reductase 1
SynonymsUNQ2423/PRO4981
MLSTD2
DescriptionFUNCTION: Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols . It plays an essential role in the production of ether lipids/plasmalogens which synthesis requires fatty alcohols . In parallel, it is also required for wax monoesters production since fatty alcohols also constitute a substrate for their synthesis (By similarity). .

FUNCTION: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. .

FUNCTION: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. .

AccessionsQ8WVX9
ENST00000532701.1
A0A8V8TQT9
E9PNW8
ENST00000532502.1
E9PPB8
ENST00000354817.8
ENST00000703358.1