Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 19 studies | 50% ± 18% | |
oligodendrocyte precursor cell | 14 studies | 49% ± 17% | |
oligodendrocyte | 12 studies | 30% ± 16% | |
GABAergic neuron | 11 studies | 52% ± 25% | |
glutamatergic neuron | 10 studies | 58% ± 21% | |
endothelial cell | 7 studies | 48% ± 21% | |
microglial cell | 7 studies | 35% ± 17% | |
retinal ganglion cell | 7 studies | 74% ± 19% | |
retinal cone cell | 7 studies | 59% ± 23% | |
interneuron | 6 studies | 60% ± 18% | |
retina horizontal cell | 6 studies | 49% ± 20% | |
cardiac muscle cell | 6 studies | 68% ± 18% | |
ciliated cell | 6 studies | 45% ± 23% | |
kidney loop of Henle epithelial cell | 5 studies | 52% ± 39% | |
renal alpha-intercalated cell | 5 studies | 61% ± 31% | |
amacrine cell | 5 studies | 44% ± 26% | |
adipocyte | 5 studies | 31% ± 7% | |
retinal rod cell | 5 studies | 43% ± 15% | |
neuron | 4 studies | 43% ± 8% | |
fibroblast | 4 studies | 36% ± 14% | |
GABAergic interneuron | 3 studies | 63% ± 22% | |
Purkinje cell | 3 studies | 63% ± 22% | |
epithelial cell | 3 studies | 50% ± 8% | |
granule cell | 3 studies | 42% ± 18% | |
GABAergic amacrine cell | 3 studies | 47% ± 1% | |
Mueller cell | 3 studies | 33% ± 11% | |
OFF-bipolar cell | 3 studies | 48% ± 24% | |
glycinergic amacrine cell | 3 studies | 50% ± 2% | |
retinal pigment epithelial cell | 3 studies | 58% ± 14% | |
ependymal cell | 3 studies | 29% ± 11% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 77% ± 32% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 90% | 357.40 | 220 / 245 | 88% | 4.36 | 441 / 502 |
kidney | 100% | 1625.54 | 89 / 89 | 74% | 4.08 | 663 / 901 |
brain | 97% | 550.10 | 2572 / 2642 | 71% | 2.07 | 504 / 705 |
adrenal gland | 99% | 817.86 | 255 / 258 | 60% | 2.02 | 137 / 230 |
thymus | 99% | 506.35 | 648 / 653 | 56% | 1.63 | 341 / 605 |
pancreas | 100% | 436.43 | 327 / 328 | 37% | 0.84 | 65 / 178 |
breast | 50% | 121.07 | 230 / 459 | 65% | 4.08 | 727 / 1118 |
stomach | 82% | 3237.48 | 294 / 359 | 19% | 0.65 | 54 / 286 |
heart | 94% | 1125.75 | 809 / 861 | 0% | 0 | 0 / 0 |
muscle | 93% | 642.16 | 749 / 803 | 0% | 0 | 0 / 0 |
skin | 52% | 146.06 | 941 / 1809 | 11% | 0.31 | 53 / 472 |
esophagus | 48% | 168.88 | 693 / 1445 | 13% | 0.42 | 23 / 183 |
bladder | 43% | 58.81 | 9 / 21 | 14% | 0.47 | 72 / 504 |
ovary | 7% | 8.87 | 13 / 180 | 49% | 1.28 | 210 / 430 |
spleen | 56% | 95.42 | 135 / 241 | 0% | 0 | 0 / 0 |
intestine | 37% | 82.60 | 355 / 966 | 15% | 0.34 | 77 / 527 |
lung | 17% | 30.13 | 99 / 578 | 22% | 0.69 | 254 / 1155 |
liver | 15% | 21.38 | 33 / 226 | 11% | 0.56 | 43 / 406 |
uterus | 4% | 9.81 | 6 / 170 | 21% | 0.67 | 97 / 459 |
eye | 0% | 0 | 0 / 0 | 11% | 0.32 | 9 / 80 |
tonsil | 0% | 0 | 0 / 0 | 7% | 0.12 | 3 / 45 |
adipose | 5% | 10.29 | 63 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 2% | 4.62 | 30 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030518 | Biological process | nuclear receptor-mediated steroid hormone signaling pathway |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0120162 | Biological process | positive regulation of cold-induced thermogenesis |
GO_0048384 | Biological process | retinoic acid receptor signaling pathway |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0003707 | Molecular function | nuclear steroid receptor activity |
GO_0004879 | Molecular function | nuclear receptor activity |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0034056 | Molecular function | estrogen response element binding |
GO_0008270 | Molecular function | zinc ion binding |
GO_0005496 | Molecular function | steroid binding |
GO_0050682 | Molecular function | AF-2 domain binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ESRRG |
Protein name | Estrogen related receptor gamma Estrogen-related receptor gamma (ERR gamma-2) (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3) |
Synonyms | NR3B3 ERRG2 KIAA0832 ERR3 |
Description | FUNCTION: Orphan receptor that acts as a transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity). Induces the expression of PERM1 in the skeletal muscle. . |
Accessions | ENST00000463665.5 [P62508-4] ENST00000459955.5 ENST00000475275.5 ENST00000361395.6 [P62508-2] ENST00000487276.5 [P62508-2] ENST00000616180.4 [P62508-2] ENST00000366938.6 [P62508-2] C9J0E3 ENST00000366940.6 [P62508-2] C9J5W9 ENST00000481543.1 ENST00000361525.7 [P62508-2] ENST00000469486.5 ENST00000673908.1 [P62508-3] ENST00000408911.8 [P62508-1] ENST00000493603.5 [P62508-2] C9JNX5 P62508 ENST00000359162.6 [P62508-2] ENST00000360012.7 [P62508-2] C9JU32 ENST00000391890.7 [P62508-2] ENST00000493748.5 [P62508-2] ENST00000366937.5 [P62508-5] |