Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 13 studies | 23% ± 8% | |
non-classical monocyte | 9 studies | 29% ± 13% | |
conventional dendritic cell | 9 studies | 25% ± 12% | |
natural killer cell | 6 studies | 17% ± 2% | |
retinal rod cell | 6 studies | 23% ± 5% | |
GABAergic neuron | 6 studies | 39% ± 18% | |
interneuron | 6 studies | 31% ± 16% | |
B cell | 5 studies | 18% ± 3% | |
dendritic cell | 5 studies | 34% ± 19% | |
classical monocyte | 5 studies | 27% ± 9% | |
naive B cell | 5 studies | 16% ± 1% | |
microglial cell | 5 studies | 21% ± 5% | |
retinal ganglion cell | 5 studies | 60% ± 24% | |
epithelial cell | 5 studies | 37% ± 21% | |
neuron | 5 studies | 32% ± 12% | |
astrocyte | 5 studies | 22% ± 5% | |
glutamatergic neuron | 5 studies | 49% ± 20% | |
oligodendrocyte precursor cell | 5 studies | 23% ± 7% | |
oligodendrocyte | 5 studies | 22% ± 4% | |
retina horizontal cell | 4 studies | 22% ± 5% | |
retinal cone cell | 4 studies | 27% ± 8% | |
fibroblast | 4 studies | 21% ± 6% | |
basal cell | 4 studies | 25% ± 9% | |
macrophage | 4 studies | 22% ± 2% | |
monocyte | 4 studies | 17% ± 1% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 17% ± 1% | |
hematopoietic precursor cell | 3 studies | 23% ± 9% | |
myeloid cell | 3 studies | 26% ± 7% | |
amacrine cell | 3 studies | 21% ± 6% | |
ciliated cell | 3 studies | 36% ± 12% | |
pericyte | 3 studies | 18% ± 2% | |
leukocyte | 3 studies | 20% ± 1% | |
group 3 innate lymphoid cell | 3 studies | 22% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1836.22 | 1445 / 1445 | 100% | 19.00 | 183 / 183 |
ovary | 100% | 1728.74 | 180 / 180 | 100% | 18.10 | 430 / 430 |
prostate | 100% | 1762.39 | 245 / 245 | 100% | 27.92 | 502 / 502 |
uterus | 100% | 1971.85 | 170 / 170 | 100% | 20.58 | 459 / 459 |
lung | 100% | 2008.72 | 577 / 578 | 100% | 19.57 | 1155 / 1155 |
bladder | 100% | 1959.24 | 21 / 21 | 100% | 19.79 | 503 / 504 |
breast | 100% | 1920.84 | 459 / 459 | 100% | 31.13 | 1115 / 1118 |
thymus | 100% | 1524.64 | 652 / 653 | 100% | 18.44 | 604 / 605 |
stomach | 100% | 1421.89 | 359 / 359 | 100% | 17.37 | 285 / 286 |
intestine | 100% | 1749.23 | 966 / 966 | 100% | 17.54 | 525 / 527 |
skin | 100% | 3642.68 | 1809 / 1809 | 99% | 22.32 | 469 / 472 |
brain | 99% | 1991.97 | 2612 / 2642 | 100% | 23.42 | 705 / 705 |
kidney | 100% | 1406.76 | 89 / 89 | 99% | 14.44 | 890 / 901 |
adrenal gland | 99% | 1344.53 | 256 / 258 | 97% | 18.09 | 223 / 230 |
liver | 97% | 818.97 | 219 / 226 | 99% | 11.21 | 401 / 406 |
pancreas | 95% | 824.12 | 313 / 328 | 99% | 17.36 | 177 / 178 |
adipose | 100% | 2080.92 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2602.75 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 24.05 | 29 / 29 |
muscle | 100% | 3210.58 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1972.20 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 19.62 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.79 | 1 / 1 |
heart | 98% | 2446.24 | 843 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 96% | 1839.70 | 893 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 84% | 7.89 | 67 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0060627 | Biological process | regulation of vesicle-mediated transport |
GO_0051301 | Biological process | cell division |
GO_0061502 | Biological process | early endosome to recycling endosome transport |
GO_0007018 | Biological process | microtubule-based movement |
GO_0090267 | Biological process | positive regulation of mitotic cell cycle spindle assembly checkpoint |
GO_0000226 | Biological process | microtubule cytoskeleton organization |
GO_0030667 | Cellular component | secretory granule membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0005874 | Cellular component | microtubule |
GO_0000922 | Cellular component | spindle pole |
GO_0016020 | Cellular component | membrane |
GO_0030666 | Cellular component | endocytic vesicle membrane |
GO_0005813 | Cellular component | centrosome |
GO_0000776 | Cellular component | kinetochore |
GO_0055038 | Cellular component | recycling endosome membrane |
GO_0005868 | Cellular component | cytoplasmic dynein complex |
GO_0005829 | Cellular component | cytosol |
GO_0101003 | Cellular component | ficolin-1-rich granule membrane |
GO_0019003 | Molecular function | GDP binding |
GO_0060090 | Molecular function | molecular adaptor activity |
GO_0005525 | Molecular function | GTP binding |
GO_0030674 | Molecular function | protein-macromolecule adaptor activity |
GO_0005524 | Molecular function | ATP binding |
GO_0003723 | Molecular function | RNA binding |
GO_0005515 | Molecular function | protein binding |
GO_0045504 | Molecular function | dynein heavy chain binding |
Gene name | DYNC1LI1 |
Protein name | Cytoplasmic dynein 1 light intermediate chain 1 (LIC1) (Dynein light chain A) (DLC-A) (Dynein light intermediate chain 1, cytosolic) (DLIC-1) Dynein light intermediate chain |
Synonyms | DNCLI1 |
Description | FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress through the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores. Forms a functional Rab11/RAB11FIP3/dynein complex onto endosomal membrane that regulates the movement of peripheral sorting endosomes (SE) along microtubule tracks toward the microtubule organizing center/centrosome, generating the endosomal recycling compartment (ERC) . . FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. . FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. . FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. . |
Accessions | C9JLW1 ENST00000432458.6 ENST00000424991.1 C9JGM7 Q9Y6G9 E9PHI6 ENST00000413350.5 ENST00000273130.9 |