DRAM2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_0007601Biological processvisual perception
GO_0045494Biological processphotoreceptor cell maintenance
GO_0006914Biological processautophagy
GO_0010506Biological processregulation of autophagy
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0016324Cellular componentapical plasma membrane
GO_0005764Cellular componentlysosome
GO_0001917Cellular componentphotoreceptor inner segment
GO_0005794Cellular componentGolgi apparatus
GO_0005765Cellular componentlysosomal membrane
GO_0005737Cellular componentcytoplasm

IV. Literature review

[source]
Gene nameDRAM2
Protein nameDNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77)
DNA damage regulated autophagy modulator 2
SynonymsUNQ154/PRO180
PSEC0031
TMEM77
DescriptionFUNCTION: Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1. .

AccessionsENST00000286692.8
Q6UX65
S4R2Z2
ENST00000484310.6
ENST00000496430.6
ENST00000539140.6