DPH6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0017183Biological processprotein histidyl modification to diphthamide
GO_0005829Cellular componentcytosol
GO_0017178Molecular functiondiphthine-ammonia ligase activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameDPH6
Protein nameDiphthine--ammonia ligase (EC 6.3.1.14) (ATP-binding domain-containing protein 4) (Diphthamide synthase) (Diphthamide synthetase) (Protein DPH6 homolog)
SynonymsATPBD4
DescriptionFUNCTION: Amidase that may catalyze the last step of diphthamide biosynthesis using ammonium and ATP . Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor (EEF2) to diphthamide (By similarity). .

AccessionsH0YNH5
ENST00000256538.9 [Q7L8W6-1]
ENST00000558266.5
ENST00000561411.1
Q7L8W6
H0YND7
ENST00000440392.3 [Q7L8W6-2]