Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| enterocyte | 7 studies | 49% ± 24% | |
| epithelial cell of proximal tubule | 6 studies | 43% ± 10% | |
| enteroendocrine cell | 3 studies | 30% ± 3% | |
| intestinal crypt stem cell | 3 studies | 28% ± 1% | |
| progenitor cell | 3 studies | 27% ± 11% | |
| epithelial cell | 3 studies | 28% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| intestine | 3 studies | 25% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 11957.61 | 328 / 328 | 85% | 38.72 | 151 / 178 |
| kidney | 100% | 12152.21 | 89 / 89 | 51% | 28.27 | 461 / 901 |
| stomach | 72% | 106.72 | 258 / 359 | 67% | 184.18 | 193 / 286 |
| intestine | 51% | 5723.42 | 493 / 966 | 81% | 260.67 | 428 / 527 |
| spleen | 100% | 401.77 | 240 / 241 | 0% | 0 | 0 / 0 |
| adrenal gland | 91% | 167.98 | 234 / 258 | 6% | 0.51 | 13 / 230 |
| ovary | 81% | 95.68 | 146 / 180 | 12% | 1.96 | 53 / 430 |
| lung | 71% | 88.14 | 411 / 578 | 22% | 7.12 | 250 / 1155 |
| thymus | 66% | 86.60 | 430 / 653 | 6% | 1.32 | 34 / 605 |
| breast | 60% | 55.93 | 274 / 459 | 12% | 0.89 | 131 / 1118 |
| skin | 56% | 132.43 | 1005 / 1809 | 7% | 0.64 | 34 / 472 |
| uterus | 44% | 59.38 | 74 / 170 | 8% | 13.57 | 36 / 459 |
| prostate | 47% | 50.00 | 115 / 245 | 3% | 0.99 | 17 / 502 |
| bladder | 19% | 17.33 | 4 / 21 | 27% | 81.77 | 138 / 504 |
| brain | 8% | 13.56 | 220 / 2642 | 28% | 4.77 | 194 / 705 |
| adipose | 35% | 42.13 | 426 / 1204 | 0% | 0 | 0 / 0 |
| liver | 19% | 14.73 | 44 / 226 | 12% | 2.15 | 50 / 406 |
| esophagus | 11% | 18.50 | 160 / 1445 | 17% | 17.71 | 32 / 183 |
| blood vessel | 13% | 22.91 | 179 / 1335 | 0% | 0 | 0 / 0 |
| heart | 13% | 8.76 | 109 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 11% | 0.73 | 5 / 45 |
| peripheral blood | 4% | 6.71 | 33 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.31 | 1 / 29 |
| muscle | 1% | 1.39 | 10 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0043154 | Biological process | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process |
| GO_0071466 | Biological process | cellular response to xenobiotic stimulus |
| GO_0006954 | Biological process | inflammatory response |
| GO_0072340 | Biological process | lactam catabolic process |
| GO_1901749 | Biological process | leukotriene D4 catabolic process |
| GO_0030593 | Biological process | neutrophil chemotaxis |
| GO_0071732 | Biological process | cellular response to nitric oxide |
| GO_0071277 | Biological process | cellular response to calcium ion |
| GO_0016999 | Biological process | antibiotic metabolic process |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0006508 | Biological process | proteolysis |
| GO_0050667 | Biological process | homocysteine metabolic process |
| GO_0006751 | Biological process | glutathione catabolic process |
| GO_0030336 | Biological process | negative regulation of cell migration |
| GO_0006749 | Biological process | glutathione metabolic process |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0031528 | Cellular component | microvillus membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0030054 | Cellular component | cell junction |
| GO_0098552 | Cellular component | side of membrane |
| GO_0045177 | Cellular component | apical part of cell |
| GO_0043027 | Molecular function | cysteine-type endopeptidase inhibitor activity involved in apoptotic process |
| GO_0034235 | Molecular function | GPI anchor binding |
| GO_0070573 | Molecular function | metallodipeptidase activity |
| GO_0072341 | Molecular function | modified amino acid binding |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0008800 | Molecular function | beta-lactamase activity |
| GO_0008235 | Molecular function | metalloexopeptidase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0016805 | Molecular function | dipeptidase activity |
| Gene name | DPEP1 |
| Protein name | Dipeptidase 1 (EC 3.4.13.19) (Beta-lactamase) (EC 3.5.2.6) (Dehydropeptidase-I) (Microsomal dipeptidase) (Renal dipeptidase) (hRDP) Dipeptidase (EC 3.4.13.19) |
| Synonyms | MDP RDP |
| Description | FUNCTION: Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4 . Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation . Possesses also beta lactamase activity and can hydrolyze the beta-lactam antibiotic imipenem . .; FUNCTION: Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver. . FUNCTION: Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver. . |
| Accessions | ENST00000261615.5 ENST00000421184.5 P16444 ENST00000690203.1 ENST00000568281.5 H3BQS5 H3BP43 ENST00000570029.5 Q6I9V1 ENST00000393092.7 |
