DNMBP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0060271Biological processcilium assembly
GO_0051056Biological processregulation of small GTPase mediated signal transduction
GO_0008360Biological processregulation of cell shape
GO_0035556Biological processintracellular signal transduction
GO_0005911Cellular componentcell-cell junction
GO_0005795Cellular componentGolgi stack
GO_0098793Cellular componentpresynapse
GO_0005856Cellular componentcytoskeleton
GO_0005829Cellular componentcytosol
GO_0045202Cellular componentsynapse
GO_0005794Cellular componentGolgi apparatus
GO_0005737Cellular componentcytoplasm
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDNMBP
Protein nameDynamin-binding protein (Scaffold protein Tuba)
SynonymsARHGEF36
TUBA
KIAA1010
DescriptionFUNCTION: Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells . Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation . Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (By similarity). .

AccessionsA0A1B0GTX1
A0A1C7CYY6
ENST00000636706.1
ENST00000324109.9 [Q6XZF7-1]
A0A2X0U4N6
Q6XZF7
ENST00000543621.6