Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 8 studies | 26% ± 9% | |
| epithelial cell | 6 studies | 31% ± 17% | |
| endothelial cell of lymphatic vessel | 6 studies | 38% ± 13% | |
| fibroblast | 5 studies | 20% ± 3% | |
| macrophage | 4 studies | 23% ± 5% | |
| ciliated cell | 3 studies | 21% ± 1% | |
| GABAergic neuron | 3 studies | 39% ± 4% | |
| glutamatergic neuron | 3 studies | 36% ± 8% | |
| transit amplifying cell | 3 studies | 33% ± 22% | |
| astrocyte | 3 studies | 26% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 27% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 100% | 3543.34 | 966 / 966 | 100% | 30.31 | 525 / 527 |
| esophagus | 100% | 2135.87 | 1445 / 1445 | 99% | 25.91 | 182 / 183 |
| prostate | 100% | 2196.78 | 245 / 245 | 99% | 19.25 | 499 / 502 |
| stomach | 100% | 3342.04 | 359 / 359 | 99% | 29.63 | 284 / 286 |
| pancreas | 100% | 2255.43 | 328 / 328 | 98% | 22.13 | 175 / 178 |
| lung | 100% | 2017.89 | 577 / 578 | 98% | 16.35 | 1127 / 1155 |
| thymus | 100% | 2111.29 | 651 / 653 | 96% | 12.45 | 579 / 605 |
| bladder | 100% | 4832.19 | 21 / 21 | 95% | 18.18 | 480 / 504 |
| uterus | 100% | 2685.37 | 170 / 170 | 94% | 13.64 | 433 / 459 |
| kidney | 100% | 2430.29 | 89 / 89 | 92% | 9.96 | 830 / 901 |
| skin | 100% | 5601.17 | 1809 / 1809 | 88% | 7.84 | 413 / 472 |
| breast | 100% | 2562.70 | 459 / 459 | 87% | 14.55 | 976 / 1118 |
| adrenal gland | 99% | 1341.06 | 255 / 258 | 79% | 6.69 | 182 / 230 |
| liver | 100% | 1317.19 | 225 / 226 | 71% | 6.99 | 290 / 406 |
| ovary | 100% | 2650.61 | 180 / 180 | 62% | 5.47 | 266 / 430 |
| brain | 66% | 561.19 | 1749 / 2642 | 96% | 12.04 | 674 / 705 |
| adipose | 100% | 3034.92 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 100% | 1847.74 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1740.57 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.62 | 1 / 1 |
| blood vessel | 100% | 1631.39 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 10.87 | 43 / 45 |
| heart | 95% | 1093.89 | 817 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 69% | 9.40 | 20 / 29 |
| peripheral blood | 68% | 1243.10 | 634 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 64% | 4.14 | 51 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0060271 | Biological process | cilium assembly |
| GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
| GO_0008360 | Biological process | regulation of cell shape |
| GO_0035556 | Biological process | intracellular signal transduction |
| GO_0005911 | Cellular component | cell-cell junction |
| GO_0005795 | Cellular component | Golgi stack |
| GO_0098793 | Cellular component | presynapse |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0005829 | Cellular component | cytosol |
| GO_0045202 | Cellular component | synapse |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | DNMBP |
| Protein name | Dynamin-binding protein (Scaffold protein Tuba) |
| Synonyms | ARHGEF36 TUBA KIAA1010 |
| Description | FUNCTION: Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells . Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation . Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (By similarity). . |
| Accessions | A0A1B0GTX1 A0A1C7CYY6 ENST00000636706.1 ENST00000324109.9 [Q6XZF7-1] A0A2X0U4N6 Q6XZF7 ENST00000543621.6 |