DNAJC5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0061077Biological processchaperone-mediated protein folding
GO_0016079Biological processsynaptic vesicle exocytosis
GO_0045055Biological processregulated exocytosis
GO_0051402Biological processneuron apoptotic process
GO_0006887Biological processexocytosis
GO_0098693Biological processregulation of synaptic vesicle cycle
GO_0043524Biological processnegative regulation of neuron apoptotic process
GO_0098793Cellular componentpresynapse
GO_0061202Cellular componentclathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
GO_0035579Cellular componentspecific granule membrane
GO_0005886Cellular componentplasma membrane
GO_0031594Cellular componentneuromuscular junction
GO_0016020Cellular componentmembrane
GO_0005739Cellular componentmitochondrion
GO_0030672Cellular componentsynaptic vesicle membrane
GO_0035577Cellular componentazurophil granule membrane
GO_0042584Cellular componentchromaffin granule membrane
GO_0005794Cellular componentGolgi apparatus
GO_0005829Cellular componentcytosol
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0042470Cellular componentmelanosome
GO_0005765Cellular componentlysosomal membrane
GO_0043008Molecular functionATP-dependent protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDNAJC5
Protein nameDnaJ homolog subfamily C member 5 (Ceroid-lipofuscinosis neuronal protein 4) (Cysteine string protein) (CSP)
SynonymsCLN4
DescriptionFUNCTION: Acts as a general chaperone in regulated exocytosis (By similarity). Acts as a co-chaperone for the SNARE protein SNAP-25 (By similarity). Involved in the calcium-mediated control of a late stage of exocytosis (By similarity). May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings (By similarity). .

AccessionsENST00000703637.1 [Q9H3Z4-2]
Q9H3Z4
ENST00000360864.9 [Q9H3Z4-1]
ENST00000470551.1 [Q9H3Z4-2]