CXCL6 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CXCL6 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	84%	278.33	276 / 328	80%	26.61	143 / 178
prostate	91%	275.45	222 / 245	44%	4.01	220 / 502
kidney	83%	271.10	74 / 89	49%	27.80	438 / 901
liver	84%	199.40	190 / 226	38%	26.42	155 / 406
lung	57%	212.20	327 / 578	55%	23.12	632 / 1155
esophagus	29%	72.29	413 / 1445	75%	27.18	138 / 183
spleen	100%	5018.56	241 / 241	0%	0	0 / 0
intestine	39%	68.47	375 / 966	49%	9.20	258 / 527
stomach	19%	18.03	70 / 359	47%	10.07	134 / 286
uterus	7%	17.48	12 / 170	51%	26.95	234 / 459
bladder	14%	18.81	3 / 21	43%	11.76	218 / 504
adipose	37%	206.09	443 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	36%	12.82	16 / 45
ovary	8%	3.51	14 / 180	27%	3.27	117 / 430
skin	28%	670.19	509 / 1809	5%	0.73	24 / 472
heart	32%	111.02	278 / 861	0%	0	0 / 0
breast	27%	25.65	122 / 459	5%	0.58	53 / 1118
peripheral blood	13%	19.01	122 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	10%	1.30	3 / 29
brain	2%	1.21	52 / 2642	7%	1.52	49 / 705
thymus	2%	1.45	16 / 653	6%	1.18	39 / 605
blood vessel	9%	9.73	117 / 1335	0%	0	0 / 0
adrenal gland	7%	6.53	17 / 258	1%	0.31	3 / 230
muscle	0%	0.30	1 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0001776	Biological process	leukocyte homeostasis
GO_0006954	Biological process	inflammatory response
GO_0007165	Biological process	signal transduction
GO_0030593	Biological process	neutrophil chemotaxis
GO_0006935	Biological process	chemotaxis
GO_0007267	Biological process	cell-cell signaling
GO_0070098	Biological process	chemokine-mediated signaling pathway
GO_0042742	Biological process	defense response to bacterium
GO_0071222	Biological process	cellular response to lipopolysaccharide
GO_0061844	Biological process	antimicrobial humoral immune response mediated by antimicrobial peptide
GO_0070951	Biological process	regulation of neutrophil mediated killing of gram-negative bacterium
GO_0042119	Biological process	neutrophil activation
GO_0032642	Biological process	regulation of chemokine production
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0008201	Molecular function	heparin binding
GO_0008009	Molecular function	chemokine activity
GO_0045236	Molecular function	CXCR chemokine receptor binding
GO_0005515	Molecular function	protein binding

Gene name	CXCL6
Protein name	C-X-C motif chemokine 6 (Chemokine alpha 3) (CKA-3) (Granulocyte chemotactic protein 2) (GCP-2) (Small-inducible cytokine B6) [Cleaved into: Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3] C-X-C motif chemokine
Synonyms	SCYB6 GCP2
Description	FUNCTION: Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7). .
Accessions	P80162 D6RF92 ENST00000515050.1 ENST00000226317.10

CXCL6 report