I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| macrophage | 3 studies | 51% ± 22% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 3 studies | 51% ± 22% |
Insufficient scRNA-seq data for expression of CXCL5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 98% | 1160.62 | 564 / 578 | 51% | 32.65 | 584 / 1155 |
| stomach | 47% | 417.24 | 167 / 359 | 69% | 161.68 | 198 / 286 |
| pancreas | 26% | 38.38 | 84 / 328 | 81% | 128.59 | 145 / 178 |
| brain | 75% | 107.50 | 1992 / 2642 | 27% | 3.98 | 193 / 705 |
| spleen | 95% | 133.90 | 229 / 241 | 0% | 0 | 0 / 0 |
| intestine | 17% | 94.64 | 166 / 966 | 57% | 60.33 | 301 / 527 |
| esophagus | 8% | 9.76 | 111 / 1445 | 55% | 47.49 | 101 / 183 |
| peripheral blood | 63% | 94.25 | 581 / 929 | 0% | 0 | 0 / 0 |
| kidney | 17% | 13.19 | 15 / 89 | 32% | 12.32 | 284 / 901 |
| bladder | 10% | 116.10 | 2 / 21 | 38% | 19.44 | 191 / 504 |
| liver | 26% | 35.46 | 59 / 226 | 18% | 10.82 | 73 / 406 |
| prostate | 30% | 140.54 | 73 / 245 | 11% | 1.90 | 54 / 502 |
| skin | 29% | 8033.71 | 531 / 1809 | 11% | 5.77 | 52 / 472 |
| uterus | 7% | 7.67 | 12 / 170 | 29% | 18.64 | 132 / 459 |
| breast | 27% | 33.97 | 126 / 459 | 8% | 2.02 | 87 / 1118 |
| tonsil | 0% | 0 | 0 / 0 | 27% | 3.31 | 12 / 45 |
| ovary | 4% | 2.16 | 7 / 180 | 21% | 4.61 | 92 / 430 |
| adipose | 19% | 62.71 | 233 / 1204 | 0% | 0 | 0 / 0 |
| heart | 17% | 33.07 | 149 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 10% | 5.83 | 25 / 258 | 2% | 8.59 | 4 / 230 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 2.57 | 3 / 29 |
| thymus | 2% | 1.61 | 15 / 653 | 7% | 0.61 | 42 / 605 |
| blood vessel | 8% | 8.57 | 110 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 1% | 0.73 | 9 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0071222 | Biological process | cellular response to lipopolysaccharide |
| GO_0007165 | Biological process | signal transduction |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0061844 | Biological process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| GO_0030593 | Biological process | neutrophil chemotaxis |
| GO_0070098 | Biological process | chemokine-mediated signaling pathway |
| GO_0006954 | Biological process | inflammatory response |
| GO_0006935 | Biological process | chemotaxis |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0045236 | Molecular function | CXCR chemokine receptor binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0008009 | Molecular function | chemokine activity |
| Gene name | CXCL5 |
| Protein name | C-X-C motif chemokine ligand 5 C-X-C motif chemokine 5 (ENA-78(1-78)) (Epithelial-derived neutrophil-activating protein 78) (Neutrophil-activating peptide ENA-78) (Small-inducible cytokine B5) [Cleaved into: ENA-78(8-78); ENA-78(9-78)] C-X-C motif chemokine |
| Synonyms | ENA78 SCYB5 hCG_16364 |
| Description | FUNCTION: Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. . |
| Accessions | P42830 ENST00000296027.5 Q6I9S7 A0AA51B0H1 |
