Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 47 studies | 45% ± 21% | |
fibroblast | 42 studies | 39% ± 17% | |
pericyte | 37 studies | 63% ± 26% | |
smooth muscle cell | 31 studies | 46% ± 18% | |
endothelial cell of lymphatic vessel | 18 studies | 41% ± 14% | |
capillary endothelial cell | 14 studies | 48% ± 20% | |
myofibroblast cell | 14 studies | 45% ± 18% | |
vein endothelial cell | 13 studies | 37% ± 15% | |
endothelial cell of vascular tree | 13 studies | 35% ± 11% | |
connective tissue cell | 12 studies | 34% ± 18% | |
type I pneumocyte | 11 studies | 30% ± 9% | |
adipocyte | 10 studies | 77% ± 14% | |
endothelial cell of artery | 8 studies | 47% ± 23% | |
cardiac muscle cell | 6 studies | 22% ± 6% | |
glomerular endothelial cell | 4 studies | 57% ± 3% | |
hepatic stellate cell | 3 studies | 52% ± 17% | |
epithelial cell of proximal tubule | 3 studies | 27% ± 12% | |
extravillous trophoblast | 3 studies | 79% ± 11% | |
glial cell | 3 studies | 32% ± 8% | |
epithelial cell | 3 studies | 31% ± 13% | |
lymphocyte | 3 studies | 29% ± 8% | |
muscle cell | 3 studies | 62% ± 12% | |
GABAergic neuron | 3 studies | 23% ± 6% | |
adventitial cell | 3 studies | 24% ± 8% | |
parietal epithelial cell | 3 studies | 37% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 98% | 42315.87 | 450 / 459 | 98% | 121.31 | 1094 / 1118 |
lung | 100% | 44113.32 | 577 / 578 | 96% | 101.87 | 1105 / 1155 |
thymus | 100% | 19049.24 | 650 / 653 | 90% | 79.28 | 547 / 605 |
intestine | 90% | 24632.23 | 869 / 966 | 92% | 102.61 | 484 / 527 |
bladder | 90% | 29288.67 | 19 / 21 | 88% | 82.77 | 444 / 504 |
uterus | 99% | 23289.11 | 168 / 170 | 77% | 86.82 | 353 / 459 |
kidney | 85% | 13244.76 | 76 / 89 | 88% | 218.56 | 790 / 901 |
esophagus | 72% | 18354.28 | 1040 / 1445 | 97% | 131.12 | 177 / 183 |
adrenal gland | 81% | 9836.39 | 208 / 258 | 83% | 96.79 | 191 / 230 |
prostate | 87% | 17554.92 | 212 / 245 | 73% | 40.91 | 367 / 502 |
stomach | 60% | 13107.75 | 217 / 359 | 97% | 123.34 | 276 / 286 |
skin | 64% | 9716.33 | 1163 / 1809 | 90% | 80.75 | 423 / 472 |
pancreas | 36% | 3170.87 | 119 / 328 | 96% | 164.97 | 171 / 178 |
ovary | 53% | 7102.31 | 95 / 180 | 77% | 48.47 | 332 / 430 |
adipose | 100% | 60999.92 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 60493.94 | 1335 / 1335 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 25.69 | 1 / 1 |
spleen | 99% | 24872.78 | 239 / 241 | 0% | 0 | 0 / 0 |
heart | 94% | 16474.27 | 811 / 861 | 0% | 0 | 0 / 0 |
liver | 10% | 1172.79 | 23 / 226 | 68% | 48.05 | 277 / 406 |
tonsil | 0% | 0 | 0 / 0 | 78% | 70.78 | 35 / 45 |
muscle | 62% | 6068.64 | 494 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 59% | 37.89 | 17 / 29 |
brain | 3% | 237.92 | 69 / 2642 | 41% | 47.83 | 292 / 705 |
eye | 0% | 0 | 0 / 0 | 16% | 5.87 | 13 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0061333 | Biological process | renal tubule morphogenesis |
GO_0030855 | Biological process | epithelial cell differentiation |
GO_0061304 | Biological process | retinal blood vessel morphogenesis |
GO_0030198 | Biological process | extracellular matrix organization |
GO_0038063 | Biological process | collagen-activated tyrosine kinase receptor signaling pathway |
GO_0007528 | Biological process | neuromuscular junction development |
GO_0071711 | Biological process | basement membrane organization |
GO_0001569 | Biological process | branching involved in blood vessel morphogenesis |
GO_0071230 | Biological process | cellular response to amino acid stimulus |
GO_0007420 | Biological process | brain development |
GO_0048514 | Biological process | blood vessel morphogenesis |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0005587 | Cellular component | collagen type IV trimer |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0005604 | Cellular component | basement membrane |
GO_0030020 | Molecular function | extracellular matrix structural constituent conferring tensile strength |
GO_0005201 | Molecular function | extracellular matrix structural constituent |
GO_0048407 | Molecular function | platelet-derived growth factor binding |
GO_0005515 | Molecular function | protein binding |
Gene name | COL4A1 |
Protein name | COL4A1 protein Collagen type IV alpha 1 chain Collagen alpha-1(IV) chain [Cleaved into: Arresten] |
Synonyms | |
Description | FUNCTION: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. .; FUNCTION: Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. . FUNCTION: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. . |
Accessions | A0A3B3ITS9 A0A3B3ISZ8 ENST00000650115.1 A0A3B3ISH5 A0A3B3ISV3 ENST00000649484.1 A0A3B3ITC8 ENST00000375820.10 [P02462-1] ENST00000650424.1 ENST00000648695.1 P02462 ENST00000648989.1 ENST00000648966.1 A0A3B3ITG7 ENST00000615732.2 A0A3B3IUD0 ENST00000543140.6 [P02462-2] ENST00000647797.1 ENST00000650566.1 A0A3B3IU02 A0A087WTY5 A5PKV2 |