Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 17 studies | 44% ± 21% | |
| endothelial cell | 15 studies | 32% ± 13% | |
| GABAergic neuron | 10 studies | 41% ± 23% | |
| oligodendrocyte precursor cell | 10 studies | 34% ± 15% | |
| oligodendrocyte | 10 studies | 31% ± 12% | |
| glutamatergic neuron | 9 studies | 45% ± 23% | |
| microglial cell | 9 studies | 33% ± 12% | |
| adipocyte | 9 studies | 25% ± 6% | |
| macrophage | 8 studies | 32% ± 12% | |
| fibroblast | 7 studies | 24% ± 7% | |
| interneuron | 6 studies | 48% ± 23% | |
| B cell | 5 studies | 23% ± 7% | |
| mast cell | 5 studies | 21% ± 3% | |
| endothelial cell of lymphatic vessel | 5 studies | 24% ± 6% | |
| club cell | 5 studies | 27% ± 8% | |
| smooth muscle cell | 5 studies | 19% ± 2% | |
| type I pneumocyte | 5 studies | 39% ± 9% | |
| type II pneumocyte | 5 studies | 35% ± 7% | |
| neuron | 4 studies | 37% ± 13% | |
| granule cell | 4 studies | 29% ± 6% | |
| epithelial cell | 4 studies | 38% ± 20% | |
| cardiac muscle cell | 4 studies | 27% ± 2% | |
| amacrine cell | 4 studies | 24% ± 8% | |
| retinal cone cell | 4 studies | 36% ± 13% | |
| myeloid cell | 4 studies | 24% ± 5% | |
| T cell | 4 studies | 20% ± 4% | |
| monocyte | 4 studies | 25% ± 6% | |
| dendritic cell | 4 studies | 19% ± 2% | |
| GABAergic interneuron | 3 studies | 37% ± 6% | |
| mesothelial cell | 3 studies | 33% ± 7% | |
| glycinergic amacrine cell | 3 studies | 21% ± 4% | |
| retinal rod cell | 3 studies | 30% ± 6% | |
| hepatocyte | 3 studies | 43% ± 20% | |
| retinal pigment epithelial cell | 3 studies | 35% ± 12% | |
| ependymal cell | 3 studies | 50% ± 21% | |
| alveolar macrophage | 3 studies | 29% ± 6% | |
| ciliated cell | 3 studies | 33% ± 5% | |
| pericyte | 3 studies | 22% ± 6% | |
| lymphocyte | 3 studies | 27% ± 7% | |
| basal cell | 3 studies | 32% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 2325.22 | 459 / 459 | 100% | 12.67 | 1118 / 1118 |
| esophagus | 100% | 2321.70 | 1445 / 1445 | 100% | 12.61 | 183 / 183 |
| intestine | 100% | 2244.61 | 966 / 966 | 100% | 9.72 | 527 / 527 |
| prostate | 100% | 2699.30 | 245 / 245 | 100% | 8.66 | 502 / 502 |
| skin | 100% | 2858.90 | 1809 / 1809 | 100% | 13.13 | 472 / 472 |
| thymus | 100% | 3415.14 | 653 / 653 | 100% | 16.68 | 605 / 605 |
| uterus | 100% | 2340.29 | 170 / 170 | 100% | 10.78 | 459 / 459 |
| bladder | 100% | 2173.76 | 21 / 21 | 100% | 9.10 | 503 / 504 |
| brain | 100% | 2896.71 | 2639 / 2642 | 100% | 16.95 | 704 / 705 |
| stomach | 100% | 1855.38 | 359 / 359 | 100% | 10.32 | 285 / 286 |
| kidney | 100% | 2971.42 | 89 / 89 | 100% | 10.50 | 897 / 901 |
| ovary | 100% | 1801.59 | 180 / 180 | 100% | 11.34 | 428 / 430 |
| lung | 100% | 3050.50 | 578 / 578 | 99% | 11.00 | 1149 / 1155 |
| pancreas | 100% | 1145.09 | 327 / 328 | 99% | 10.12 | 177 / 178 |
| adrenal gland | 100% | 2778.34 | 258 / 258 | 98% | 9.24 | 225 / 230 |
| liver | 100% | 1866.74 | 226 / 226 | 96% | 6.38 | 390 / 406 |
| adipose | 100% | 2179.06 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 10.27 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 16.74 | 29 / 29 |
| muscle | 100% | 2539.64 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2780.07 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 11.47 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.52 | 1 / 1 |
| blood vessel | 100% | 1835.68 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 1997.03 | 850 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 96% | 1898.21 | 891 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1901096 | Biological process | regulation of autophagosome maturation |
| GO_0006914 | Biological process | autophagy |
| GO_0016197 | Biological process | endosomal transport |
| GO_1901097 | Biological process | negative regulation of autophagosome maturation |
| GO_1904263 | Biological process | positive regulation of TORC1 signaling |
| GO_0008333 | Biological process | endosome to lysosome transport |
| GO_0009267 | Biological process | cellular response to starvation |
| GO_0036020 | Cellular component | endolysosome membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0031982 | Cellular component | vesicle |
| GO_0005770 | Cellular component | late endosome |
| GO_0003674 | Molecular function | molecular_function |
| Gene name | CLEC16A |
| Protein name | C-type lectin domain containing 16A Protein CLEC16A (C-type lectin domain family 16 member A) C-type lectin domain containing 16A (KIAA0350 protein, isoform CRA_b) |
| Synonyms | hCG_1787643 KIAA0350 |
| Description | FUNCTION: Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PRKN pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PRKN pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteasomal degradation, RNF41/NRDP1 which regulates proteasomal degradation of PRKN. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health. . |
| Accessions | A0A8V8TR67 ENST00000409552.4 [Q2KHT3-2] H7BZI2 ENST00000261657.5 H7BZJ9 ENST00000459723.1 ENST00000703130.1 ENST00000428742.6 A0A2R8YDG4 ENST00000436973.5 Q2KHT3 H7BXG1 ENST00000409790.6 [Q2KHT3-1] |