CGB3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CGB3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CGB3 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0006915Biological processapoptotic process
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007292Biological processfemale gamete generation
GO_0007267Biological processcell-cell signaling
GO_0009755Biological processhormone-mediated signaling pathway
GO_0061696Cellular componentpituitary gonadotropin complex
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0005737Cellular componentcytoplasm
GO_0005179Molecular functionhormone activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCGB3
Protein nameChorionic gonadotropin beta subunit 3 (Chorionic gonadotropin beta subunit 4)
Choriogonadotropin subunit beta 3 (Choriogonadotropin subunit beta) (CG-beta) (Chorionic gonadotropin chain beta)
SynonymsCGB5;
CGB4
CGB;
CGB8
DescriptionFUNCTION: Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. .

AccessionsENST00000448456.4 [P0DN86-1]
P0DN86
ENST00000357383.4 [P0DN86-1]
ENST00000301408.7 [P0DN86-1]
A0A0F7RQP8