CERS4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030148Biological processsphingolipid biosynthetic process
GO_0046513Biological processceramide biosynthetic process
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0003677Molecular functionDNA binding
GO_0050291Molecular functionsphingosine N-acyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCERS4
Protein nameCeramide synthase 4
Ceramide synthase 4 (CerS4) (EC 2.3.1.-) (LAG1 longevity assurance homolog 4) (Sphingosine N-acyltransferase CERS4) (EC 2.3.1.24)
SynonymsLASS4
DescriptionFUNCTION: Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl donor. .

AccessionsENST00000561008.5
H0YMY6
H0YKR4
H0YNR6
ENST00000251363.10
H0YKS3
ENST00000558268.5
H0YN04
ENST00000561053.5
ENST00000558331.5
ENST00000558877.1
H0YLY3
ENST00000560412.1
H0YKC9
ENST00000559336.5
Q9HA82
ENST00000559450.5