CEACAM5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_2000811Biological processnegative regulation of anoikis
GO_0034109Biological processhomotypic cell-cell adhesion
GO_0010832Biological processnegative regulation of myotube differentiation
GO_0043066Biological processnegative regulation of apoptotic process
GO_0007156Biological processhomophilic cell adhesion via plasma membrane adhesion molecules
GO_0006915Biological processapoptotic process
GO_0007157Biological processheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO_0016324Cellular componentapical plasma membrane
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0070062Cellular componentextracellular exosome
GO_0009986Cellular componentcell surface
GO_0098552Cellular componentside of membrane
GO_0016323Cellular componentbasolateral plasma membrane
GO_0042803Molecular functionprotein homodimerization activity
GO_0034235Molecular functionGPI anchor binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCEACAM5
Protein nameCEA cell adhesion molecule 5
Carcinoembryonic antigen-related cell adhesion molecule 5
Carcinoembryonic antigen-related cell adhesion molecule 5 isoform 3D
Carcinoembryonic antigen-related cell adhesion molecule 5 (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD antigen CD66e)
Carcinoembryonic antigen-related cell adhesion molecule 5 isoform 5D
SynonymshCG_1642477
CEA
DescriptionFUNCTION: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression . Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 . Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells . .; FUNCTION: (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. .

AccessionsQ8N4D0
ENST00000617332
M0QX98
ENST00000617332.4 [P06731-1]
ENST00000595113.1
ENST00000398599.8 [P06731-2]
P06731
ENST00000405816.5 [P06731-1]
A0A024R0K5
A0A087WYX0
M0R3J1
ENST00000595403.1
T2HUW8
ENST00000615021.4
T2HVB7
ENST00000221992.11 [P06731-1]