Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| natural killer cell | 9 studies | 19% ± 3% | |
| endothelial cell | 7 studies | 22% ± 4% | |
| CD16-positive, CD56-dim natural killer cell, human | 6 studies | 18% ± 2% | |
| epithelial cell | 6 studies | 27% ± 16% | |
| CD16-negative, CD56-bright natural killer cell, human | 5 studies | 18% ± 2% | |
| CD8-positive, alpha-beta T cell | 5 studies | 18% ± 2% | |
| B cell | 4 studies | 17% ± 1% | |
| classical monocyte | 4 studies | 19% ± 4% | |
| mature NK T cell | 4 studies | 17% ± 1% | |
| dendritic cell | 4 studies | 25% ± 7% | |
| non-classical monocyte | 3 studies | 20% ± 4% | |
| capillary endothelial cell | 3 studies | 15% ± 0% | |
| myeloid cell | 3 studies | 22% ± 5% | |
| ciliated cell | 3 studies | 26% ± 9% | |
| CD8-positive, alpha-beta memory T cell | 3 studies | 19% ± 5% | |
| macrophage | 3 studies | 17% ± 1% | |
| plasmacytoid dendritic cell | 3 studies | 21% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2860.28 | 1445 / 1445 | 100% | 37.77 | 183 / 183 |
| ovary | 100% | 2630.59 | 180 / 180 | 100% | 28.17 | 430 / 430 |
| skin | 100% | 2787.89 | 1809 / 1809 | 100% | 38.99 | 472 / 472 |
| stomach | 100% | 2193.18 | 359 / 359 | 100% | 34.38 | 286 / 286 |
| brain | 100% | 2176.27 | 2640 / 2642 | 100% | 38.37 | 705 / 705 |
| thymus | 100% | 2728.00 | 653 / 653 | 100% | 34.88 | 604 / 605 |
| intestine | 100% | 3473.58 | 966 / 966 | 100% | 35.23 | 526 / 527 |
| prostate | 100% | 2653.83 | 245 / 245 | 100% | 28.39 | 501 / 502 |
| uterus | 100% | 2931.72 | 170 / 170 | 100% | 39.50 | 458 / 459 |
| pancreas | 100% | 1597.61 | 327 / 328 | 100% | 32.35 | 178 / 178 |
| lung | 100% | 3370.39 | 578 / 578 | 100% | 30.04 | 1150 / 1155 |
| kidney | 100% | 1893.75 | 89 / 89 | 99% | 21.16 | 894 / 901 |
| bladder | 100% | 3016.76 | 21 / 21 | 99% | 33.26 | 500 / 504 |
| adrenal gland | 100% | 2175.70 | 258 / 258 | 99% | 19.41 | 228 / 230 |
| breast | 100% | 2559.61 | 459 / 459 | 99% | 29.30 | 1106 / 1118 |
| liver | 100% | 1306.00 | 226 / 226 | 98% | 17.15 | 397 / 406 |
| adipose | 100% | 2505.83 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2493.36 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 36.17 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 39.77 | 29 / 29 |
| muscle | 100% | 4043.99 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3703.90 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 35.61 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 23.77 | 1 / 1 |
| heart | 99% | 1770.72 | 856 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 2072.53 | 916 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0050684 | Biological process | regulation of mRNA processing |
| GO_0006915 | Biological process | apoptotic process |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0000278 | Biological process | mitotic cell cycle |
| GO_0001558 | Biological process | regulation of cell growth |
| GO_0007346 | Biological process | regulation of mitotic cell cycle |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0004674 | Molecular function | protein serine/threonine kinase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0106310 | Molecular function | protein serine kinase activity |
| GO_0004672 | Molecular function | protein kinase activity |
| GO_0004693 | Molecular function | cyclin-dependent protein serine/threonine kinase activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | CDK11B |
| Protein name | Cyclin dependent kinase 11B Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) |
| Synonyms | PITSLREA CDK11 PK58 CDC2L1 |
| Description | FUNCTION: Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression. . |
| Accessions | ENST00000611150.3 A0A0D9SER5 A0A0D9SEI3 ENST00000615951.4 A0A087X1I0 P21127 ENST00000340677.9 [P21127-9] ENST00000341832.11 [P21127-2] ENST00000626918.2 ENST00000629312.2 A0A0D9SEN2 ENST00000407249.7 [P21127-1] ENST00000629289.2 A0A087WYI9 |