CDC14A report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDC14A at tissue level.

III. Associated gene sets

GO_0060271Biological processcilium assembly
GO_0007605Biological processsensory perception of sound
GO_0007096Biological processregulation of exit from mitosis
GO_0051301Biological processcell division
GO_0000226Biological processmicrotubule cytoskeleton organization
GO_0032467Biological processpositive regulation of cytokinesis
GO_0060091Cellular componentkinocilium
GO_0005730Cellular componentnucleolus
GO_0000922Cellular componentspindle pole
GO_0072686Cellular componentmitotic spindle
GO_0005813Cellular componentcentrosome
GO_0005654Cellular componentnucleoplasm
GO_1902636Cellular componentkinociliary basal body
GO_0016604Cellular componentnuclear body
GO_0005829Cellular componentcytosol
GO_0032426Cellular componentstereocilium tip
GO_0005737Cellular componentcytoplasm
GO_0017018Molecular functionmyosin phosphatase activity
GO_0004722Molecular functionprotein serine/threonine phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene nameCDC14A
Protein nameCell division cycle 14A
Dual specificity protein phosphatase CDC14A (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog A)
Synonyms
DescriptionFUNCTION: Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis. Required for normal hearing . .

AccessionsA0A2R8Y6L0
ENST00000370124.8 [Q9UNH5-3]
A0A2R8Y3W8
A0A2R8YGM0
ENST00000647005.1
ENST00000635056.2
ENST00000646665.1
ENST00000647203.1
ENST00000644813.1 [Q9UNH5-5]
A0A2R8YDJ8
C9JSP6
ENST00000361544.11 [Q9UNH5-2]
A0A2R8Y5L8
ENST00000336454.5 [Q9UNH5-1]
ENST00000644676.1
ENST00000455467.6
A0A2R8YEK7
A0A0U1RQX7
ENST00000646563.1
Q9UNH5
ENST00000644844.1