Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 7 studies | 26% ± 6% |
Insufficient scRNA-seq data for expression of CD200R1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 96% | 118.72 | 554 / 578 | 74% | 2.05 | 857 / 1155 |
esophagus | 94% | 164.54 | 1355 / 1445 | 74% | 2.07 | 135 / 183 |
breast | 86% | 72.08 | 396 / 459 | 56% | 1.35 | 621 / 1118 |
bladder | 95% | 94.29 | 20 / 21 | 37% | 1.02 | 185 / 504 |
thymus | 87% | 78.19 | 571 / 653 | 40% | 0.93 | 240 / 605 |
intestine | 88% | 88.18 | 846 / 966 | 32% | 0.74 | 169 / 527 |
stomach | 70% | 38.14 | 251 / 359 | 49% | 1.27 | 140 / 286 |
skin | 72% | 89.22 | 1307 / 1809 | 46% | 1.36 | 218 / 472 |
uterus | 68% | 35.75 | 116 / 170 | 44% | 1.36 | 202 / 459 |
spleen | 100% | 539.15 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 95% | 155.08 | 1146 / 1204 | 0% | 0 | 0 / 0 |
ovary | 31% | 14.54 | 55 / 180 | 63% | 1.34 | 271 / 430 |
kidney | 38% | 27.57 | 34 / 89 | 54% | 2.34 | 488 / 901 |
prostate | 76% | 47.67 | 187 / 245 | 15% | 0.25 | 75 / 502 |
adrenal gland | 69% | 42.54 | 178 / 258 | 22% | 0.80 | 51 / 230 |
peripheral blood | 91% | 202.21 | 846 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 83% | 8.62 | 24 / 29 |
liver | 65% | 39.59 | 147 / 226 | 15% | 0.33 | 62 / 406 |
tonsil | 0% | 0 | 0 / 0 | 71% | 1.96 | 32 / 45 |
blood vessel | 71% | 49.68 | 942 / 1335 | 0% | 0 | 0 / 0 |
brain | 54% | 23.53 | 1414 / 2642 | 8% | 0.17 | 55 / 705 |
pancreas | 12% | 3.53 | 38 / 328 | 40% | 0.90 | 72 / 178 |
heart | 42% | 19.73 | 362 / 861 | 0% | 0 | 0 / 0 |
muscle | 19% | 6.42 | 151 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 10% | 0.23 | 8 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0038093 | Biological process | Fc receptor signaling pathway |
GO_0007165 | Biological process | signal transduction |
GO_0032715 | Biological process | negative regulation of interleukin-6 production |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0034113 | Biological process | heterotypic cell-cell adhesion |
GO_0150077 | Biological process | regulation of neuroinflammatory response |
GO_2000405 | Biological process | negative regulation of T cell migration |
GO_1905522 | Biological process | negative regulation of macrophage migration |
GO_0150079 | Biological process | negative regulation of neuroinflammatory response |
GO_0009986 | Cellular component | cell surface |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0043235 | Cellular component | receptor complex |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0140081 | Molecular function | glycosylated region protein binding |
GO_0038023 | Molecular function | signaling receptor activity |
GO_0019763 | Molecular function | immunoglobulin receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | CD200R1 |
Protein name | Cell surface glycoprotein CD200 receptor 1 (CD200 cell surface glycoprotein receptor) (Cell surface glycoprotein OX2 receptor 1) CD200R1 protein CD200 receptor 1 |
Synonyms | CRTR2 UNQ2522/PRO6015 MOX2R CD200R OX2R |
Description | FUNCTION: Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. . |
Accessions | ENST00000471858.5 [Q8TD46-1] ENST00000440122.6 [Q8TD46-2] ENST00000295863.4 Q8TD46 ENST00000490004.1 [Q8TD46-3] B7ZKV2 H9KV32 ENST00000308611.8 [Q8TD46-4] |