CD200R1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CD200R1 at tissue level.

III. Associated gene sets

GO_0038093Biological processFc receptor signaling pathway
GO_0007165Biological processsignal transduction
GO_0032715Biological processnegative regulation of interleukin-6 production
GO_0035556Biological processintracellular signal transduction
GO_0034113Biological processheterotypic cell-cell adhesion
GO_0150077Biological processregulation of neuroinflammatory response
GO_2000405Biological processnegative regulation of T cell migration
GO_1905522Biological processnegative regulation of macrophage migration
GO_0150079Biological processnegative regulation of neuroinflammatory response
GO_0009986Cellular componentcell surface
GO_0009897Cellular componentexternal side of plasma membrane
GO_0043235Cellular componentreceptor complex
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0140081Molecular functionglycosylated region protein binding
GO_0038023Molecular functionsignaling receptor activity
GO_0019763Molecular functionimmunoglobulin receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCD200R1
Protein nameCell surface glycoprotein CD200 receptor 1 (CD200 cell surface glycoprotein receptor) (Cell surface glycoprotein OX2 receptor 1)
CD200R1 protein
CD200 receptor 1
SynonymsCRTR2
UNQ2522/PRO6015
MOX2R
CD200R
OX2R
DescriptionFUNCTION: Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. .

AccessionsENST00000471858.5 [Q8TD46-1]
ENST00000440122.6 [Q8TD46-2]
ENST00000295863.4
Q8TD46
ENST00000490004.1 [Q8TD46-3]
B7ZKV2
H9KV32
ENST00000308611.8 [Q8TD46-4]