CCRL2 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CCRL2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	916.39	578 / 578	86%	6.87	997 / 1155
breast	99%	670.88	456 / 459	81%	4.02	903 / 1118
intestine	75%	310.21	722 / 966	98%	14.17	519 / 527
stomach	69%	94.74	249 / 359	98%	13.20	281 / 286
bladder	81%	132.67	17 / 21	78%	7.73	395 / 504
kidney	75%	103.67	67 / 89	81%	7.13	732 / 901
thymus	84%	109.74	547 / 653	60%	2.51	365 / 605
pancreas	37%	49.42	122 / 328	91%	9.16	162 / 178
uterus	75%	86.60	127 / 170	51%	2.46	232 / 459
esophagus	37%	37.10	529 / 1445	66%	5.72	120 / 183
adipose	100%	771.67	1204 / 1204	0%	0	0 / 0
spleen	100%	697.95	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	3.52	1 / 1
lymph node	0%	0	0 / 0	97%	19.24	28 / 29
brain	27%	31.25	721 / 2642	65%	3.10	458 / 705
peripheral blood	87%	440.94	804 / 929	0%	0	0 / 0
adrenal gland	53%	57.51	137 / 258	30%	1.51	70 / 230
heart	76%	91.12	654 / 861	0%	0	0 / 0
prostate	49%	52.54	119 / 245	22%	0.61	108 / 502
skin	21%	22.17	377 / 1809	47%	2.48	224 / 472
tonsil	0%	0	0 / 0	64%	2.87	29 / 45
ovary	18%	20.12	32 / 180	43%	1.55	186 / 430
blood vessel	53%	94.47	711 / 1335	0%	0	0 / 0
liver	18%	19.65	41 / 226	31%	1.38	126 / 406
muscle	27%	25.51	213 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	10%	0.30	8 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006955	Biological process	immune response
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0070098	Biological process	chemokine-mediated signaling pathway
GO_0007204	Biological process	positive regulation of cytosolic calcium ion concentration
GO_0006954	Biological process	inflammatory response
GO_0006935	Biological process	chemotaxis
GO_0019722	Biological process	calcium-mediated signaling
GO_0060326	Biological process	cell chemotaxis
GO_0009897	Cellular component	external side of plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0048020	Molecular function	CCR chemokine receptor binding
GO_0016493	Molecular function	C-C chemokine receptor activity
GO_0019957	Molecular function	C-C chemokine binding
GO_0004950	Molecular function	chemokine receptor activity
GO_0042379	Molecular function	chemokine receptor binding

Gene name	CCRL2
Protein name	C-C motif chemokine receptor like 2 Chemokine (C-C motif) receptor-like 2, isoform CRA_a (cDNA, FLJ93826, highly similar to Homo sapiens chemokine (C-C motif) receptor-like 2 (CCRL2), mRNA) C-C chemokine receptor-like 2 (Chemokine receptor CCR11) (Chemokine receptor X) (Putative MCP-1 chemokine receptor)
Synonyms	CRAM HCR CCR11 CCR6 CKRX hCG_15322
Description	FUNCTION: Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses.
Accessions	ENST00000399036.4 [O00421-1] ENST00000433848.1 B2R8C0 ENST00000400882.2 [O00421-1] C9JP23 ENST00000400880.3 [O00421-1] O00421 ENST00000357392.4 [O00421-2]

CCRL2 report