Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 9 studies | 25% ± 6% | |
| pericyte | 8 studies | 27% ± 6% | |
| epithelial cell | 7 studies | 34% ± 17% | |
| smooth muscle cell | 7 studies | 25% ± 6% | |
| myofibroblast cell | 6 studies | 28% ± 7% | |
| connective tissue cell | 6 studies | 26% ± 5% | |
| hematopoietic stem cell | 5 studies | 25% ± 4% | |
| basal cell | 5 studies | 24% ± 12% | |
| B cell | 4 studies | 23% ± 2% | |
| progenitor cell | 4 studies | 30% ± 9% | |
| kidney distal convoluted tubule epithelial cell | 4 studies | 29% ± 5% | |
| intestinal crypt stem cell | 4 studies | 19% ± 4% | |
| endothelial cell | 4 studies | 23% ± 9% | |
| hematopoietic precursor cell | 3 studies | 35% ± 20% | |
| conventional dendritic cell | 3 studies | 33% ± 15% | |
| neural crest cell | 3 studies | 34% ± 9% | |
| cardiac muscle cell | 3 studies | 20% ± 3% | |
| neuron | 3 studies | 28% ± 12% | |
| dendritic cell | 3 studies | 35% ± 13% | |
| megakaryocyte-erythroid progenitor cell | 3 studies | 42% ± 21% | |
| naive B cell | 3 studies | 18% ± 2% | |
| plasmacytoid dendritic cell | 3 studies | 28% ± 5% | |
| oligodendrocyte precursor cell | 3 studies | 27% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 2936.57 | 21 / 21 | 100% | 38.86 | 504 / 504 |
| esophagus | 100% | 2313.81 | 1445 / 1445 | 100% | 31.78 | 183 / 183 |
| ovary | 100% | 6292.73 | 180 / 180 | 100% | 53.03 | 430 / 430 |
| thymus | 100% | 3060.22 | 653 / 653 | 100% | 48.47 | 605 / 605 |
| prostate | 100% | 2831.10 | 245 / 245 | 100% | 26.29 | 501 / 502 |
| lung | 100% | 2615.87 | 576 / 578 | 100% | 34.78 | 1154 / 1155 |
| uterus | 100% | 3889.40 | 170 / 170 | 100% | 36.56 | 457 / 459 |
| kidney | 100% | 2974.62 | 89 / 89 | 100% | 36.02 | 897 / 901 |
| breast | 100% | 2568.10 | 459 / 459 | 100% | 28.17 | 1113 / 1118 |
| intestine | 100% | 2223.30 | 966 / 966 | 99% | 44.26 | 524 / 527 |
| brain | 99% | 1585.42 | 2628 / 2642 | 100% | 40.71 | 704 / 705 |
| stomach | 100% | 1755.01 | 359 / 359 | 99% | 34.91 | 283 / 286 |
| skin | 100% | 2420.08 | 1809 / 1809 | 99% | 41.07 | 467 / 472 |
| pancreas | 97% | 1810.07 | 319 / 328 | 99% | 27.59 | 177 / 178 |
| adrenal gland | 100% | 1268.33 | 258 / 258 | 96% | 26.48 | 221 / 230 |
| liver | 98% | 1804.91 | 222 / 226 | 91% | 25.90 | 368 / 406 |
| adipose | 100% | 2227.56 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3125.22 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 67.67 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 28.99 | 29 / 29 |
| muscle | 100% | 2315.52 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1436.46 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 29.62 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 21.02 | 1 / 1 |
| heart | 99% | 2836.67 | 854 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 55% | 1373.57 | 511 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007131 | Biological process | reciprocal meiotic recombination |
| GO_0016567 | Biological process | protein ubiquitination |
| GO_0051026 | Biological process | chiasma assembly |
| GO_0001825 | Biological process | blastocyst formation |
| GO_0007286 | Biological process | spermatid development |
| GO_0000795 | Cellular component | synaptonemal complex |
| GO_0061630 | Molecular function | ubiquitin protein ligase activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | CCNB1IP1 |
| Protein name | E3 ubiquitin-protein ligase CCNB1IP1 (EC 2.3.2.27) (Cyclin-B1-interacting protein 1) (Human enhancer of invasion 10) (RING-type E3 ubiquitin transferase CCNB1IP1) Cyclin B1 interacting protein 1 Cyclin B1 interacting protein 1 (Epididymis secretory sperm binding protein) |
| Synonyms | C14orf18 HEI10 hCG_40484 |
| Description | FUNCTION: Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL-gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis. .; FUNCTION: E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis. |
| Accessions | Q9NPC3 ENST00000708737.1 ENST00000398163.6 ENST00000353689.8 ENST00000554047.1 ENST00000398169.7 ENST00000708741.1 ENST00000708742.1 ENST00000557665.5 ENST00000398160.6 G3V5Q4 ENST00000556854.5 ENST00000556563.5 G3V5S3 ENST00000554184.5 H0YJB2 H0YJ70 ENST00000708738.1 ENST00000708739.1 ENST00000708740.1 ENST00000358932.9 A0A384MR52 G3V5E6 |