CCL8 | OmnibusX

Name	Number of supported studies	Average coverage
pericyte	4 studies	18% ± 2%	Explore
fibroblast	3 studies	31% ± 11%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CCL8 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	91%	142.68	418 / 459	80%	19.37	897 / 1118
lung	82%	119.43	473 / 578	79%	15.09	918 / 1155
thymus	85%	90.69	558 / 653	51%	3.91	307 / 605
adrenal gland	91%	95.99	235 / 258	41%	7.08	95 / 230
intestine	82%	284.23	793 / 966	49%	6.38	257 / 527
kidney	70%	72.11	62 / 89	57%	7.21	518 / 901
skin	51%	36.36	919 / 1809	72%	17.15	340 / 472
ovary	38%	16.16	68 / 180	83%	16.83	357 / 430
stomach	56%	41.46	202 / 359	56%	8.36	161 / 286
uterus	35%	14.96	59 / 170	64%	10.84	294 / 459
adipose	91%	233.89	1092 / 1204	0%	0	0 / 0
bladder	29%	85.24	6 / 21	58%	12.72	294 / 504
esophagus	42%	27.95	600 / 1445	45%	7.02	83 / 183
lymph node	0%	0	0 / 0	83%	60.09	24 / 29
tonsil	0%	0	0 / 0	67%	9.72	30 / 45
blood vessel	63%	87.13	847 / 1335	0%	0	0 / 0
pancreas	10%	3.76	33 / 328	47%	5.48	83 / 178
spleen	52%	25.76	125 / 241	0%	0	0 / 0
heart	51%	48.02	442 / 861	0%	0	0 / 0
prostate	29%	25.76	71 / 245	19%	1.19	97 / 502
liver	12%	5.95	26 / 226	35%	2.95	142 / 406
brain	13%	14.98	346 / 2642	31%	4.53	217 / 705
muscle	14%	9.55	113 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	13%	0.78	10 / 80
peripheral blood	4%	3.20	39 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0001525	Biological process	angiogenesis
GO_0006954	Biological process	inflammatory response
GO_0043547	Biological process	positive regulation of GTPase activity
GO_0007165	Biological process	signal transduction
GO_0009615	Biological process	response to virus
GO_0006935	Biological process	chemotaxis
GO_0006874	Biological process	intracellular calcium ion homeostasis
GO_0044828	Biological process	negative regulation by host of viral genome replication
GO_0007267	Biological process	cell-cell signaling
GO_0070098	Biological process	chemokine-mediated signaling pathway
GO_0006887	Biological process	exocytosis
GO_0030335	Biological process	positive regulation of cell migration
GO_0070664	Biological process	negative regulation of leukocyte proliferation
GO_0048245	Biological process	eosinophil chemotaxis
GO_0002687	Biological process	positive regulation of leukocyte migration
GO_0061844	Biological process	antimicrobial humoral immune response mediated by antimicrobial peptide
GO_0002548	Biological process	monocyte chemotaxis
GO_0006816	Biological process	calcium ion transport
GO_0005615	Cellular component	extracellular space
GO_0008201	Molecular function	heparin binding
GO_0016004	Molecular function	phospholipase activator activity
GO_0008009	Molecular function	chemokine activity
GO_0048020	Molecular function	CCR chemokine receptor binding
GO_0031727	Molecular function	CCR2 chemokine receptor binding
GO_0004672	Molecular function	protein kinase activity
GO_0005515	Molecular function	protein binding

Gene name	CCL8
Protein name	C-C motif chemokine 8 (HC14) (Monocyte chemoattractant protein 2) (Monocyte chemotactic protein 2) (MCP-2) (Small-inducible cytokine A8) [Cleaved into: MCP-2(6-76)]
Synonyms	SCYA10 MCP2 SCYA8
Description	FUNCTION: Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. .
Accessions	ENST00000394620.2 P80075

CCL8 report