Insufficient scRNA-seq data for expression of CCL7 at single-cell level.
Insufficient scRNA-seq data for expression of CCL7 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 49% | 27.12 | 283 / 578 | 59% | 3.40 | 682 / 1155 |
| skin | 32% | 21.03 | 576 / 1809 | 35% | 1.89 | 166 / 472 |
| ovary | 8% | 1.09 | 15 / 180 | 58% | 3.15 | 248 / 430 |
| intestine | 27% | 7.67 | 258 / 966 | 31% | 1.28 | 163 / 527 |
| bladder | 19% | 35.33 | 4 / 21 | 33% | 2.09 | 168 / 504 |
| stomach | 17% | 6.31 | 61 / 359 | 35% | 1.34 | 101 / 286 |
| breast | 17% | 3.96 | 78 / 459 | 34% | 2.35 | 375 / 1118 |
| adrenal gland | 44% | 7.70 | 113 / 258 | 4% | 0.29 | 10 / 230 |
| uterus | 8% | 1.77 | 13 / 170 | 39% | 1.60 | 179 / 459 |
| pancreas | 9% | 1.17 | 28 / 328 | 34% | 1.26 | 60 / 178 |
| adipose | 40% | 16.15 | 482 / 1204 | 0% | 0 | 0 / 0 |
| prostate | 32% | 7.30 | 79 / 245 | 6% | 0.12 | 31 / 502 |
| esophagus | 7% | 1.50 | 106 / 1445 | 30% | 1.38 | 54 / 183 |
| kidney | 28% | 5.06 | 25 / 89 | 7% | 0.26 | 67 / 901 |
| thymus | 12% | 2.14 | 80 / 653 | 21% | 0.46 | 126 / 605 |
| lymph node | 0% | 0 | 0 / 0 | 28% | 2.40 | 8 / 29 |
| blood vessel | 23% | 6.80 | 312 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 18% | 0.52 | 8 / 45 |
| heart | 17% | 5.77 | 149 / 861 | 0% | 0 | 0 / 0 |
| brain | 2% | 2.65 | 54 / 2642 | 12% | 0.93 | 82 / 705 |
| liver | 8% | 2.55 | 19 / 226 | 3% | 0.15 | 12 / 406 |
| peripheral blood | 11% | 4.32 | 100 / 929 | 0% | 0 | 0 / 0 |
| spleen | 3% | 1.07 | 8 / 241 | 0% | 0 | 0 / 0 |
| muscle | 1% | 0.07 | 7 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006954 | Biological process | inflammatory response |
| GO_0043547 | Biological process | positive regulation of GTPase activity |
| GO_0071361 | Biological process | cellular response to ethanol |
| GO_0010332 | Biological process | response to gamma radiation |
| GO_0007165 | Biological process | signal transduction |
| GO_0006935 | Biological process | chemotaxis |
| GO_0006874 | Biological process | intracellular calcium ion homeostasis |
| GO_0007010 | Biological process | cytoskeleton organization |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_0070098 | Biological process | chemokine-mediated signaling pathway |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_2000503 | Biological process | positive regulation of natural killer cell chemotaxis |
| GO_0048245 | Biological process | eosinophil chemotaxis |
| GO_0061844 | Biological process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| GO_0008360 | Biological process | regulation of cell shape |
| GO_0002548 | Biological process | monocyte chemotaxis |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0008201 | Molecular function | heparin binding |
| GO_0031726 | Molecular function | CCR1 chemokine receptor binding |
| GO_0008009 | Molecular function | chemokine activity |
| GO_0048020 | Molecular function | CCR chemokine receptor binding |
| GO_0031727 | Molecular function | CCR2 chemokine receptor binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CCL7 |
| Protein name | C-C motif chemokine ligand 7 C-C motif chemokine C-C motif chemokine 7 (Monocyte chemoattractant protein 3) (Monocyte chemotactic protein 3) (MCP-3) (NC28) (Small-inducible cytokine A7) |
| Synonyms | MCP-3 hCG_29304 SCYA7 SCYA6 MCP3 |
| Description | FUNCTION: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. |
| Accessions | Q7Z7Q8 ENST00000378569.2 P80098 A8MX17 ENST00000394630.3 ENST00000394627.5 A8MVH1 |