CCL23 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CCL23 at tissue level.

III. Associated gene sets

GO_0008285Biological processnegative regulation of cell population proliferation
GO_0006954Biological processinflammatory response
GO_0043547Biological processpositive regulation of GTPase activity
GO_0007165Biological processsignal transduction
GO_0006935Biological processchemotaxis
GO_0006874Biological processintracellular calcium ion homeostasis
GO_0007267Biological processcell-cell signaling
GO_0006955Biological processimmune response
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0070098Biological processchemokine-mediated signaling pathway
GO_0030335Biological processpositive regulation of cell migration
GO_0048245Biological processeosinophil chemotaxis
GO_0061844Biological processantimicrobial humoral immune response mediated by antimicrobial peptide
GO_0002548Biological processmonocyte chemotaxis
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0008201Molecular functionheparin binding
GO_0031726Molecular functionCCR1 chemokine receptor binding
GO_0008009Molecular functionchemokine activity
GO_0048020Molecular functionCCR chemokine receptor binding

IV. Literature review

[source]
Gene nameCCL23
Protein nameC-C motif chemokine 23 (CK-beta-8) (CKB-8) (Macrophage inflammatory protein 3) (MIP-3) (Myeloid progenitor inhibitory factor 1) (MPIF-1) (Small-inducible cytokine A23) [Cleaved into: CCL23(19-99); CCL23(22-99); CCL23(27-99); CCL23(30-99)]
C-C motif chemokine 23 (C-C motif chemokine ligand 23)
SynonymsMIP3
MPIF1
SCYA23
DescriptionFUNCTION: Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than CCL23. .

AccessionsENST00000615050.2 [P55773-2]
P55773
ENST00000631414.1
ENST00000610342.2
ENST00000632633.1
ENST00000612516.4 [P55773-1]
ENST00000613876.1
A0A087WV09