Name | Number of supported studies | Average coverage | |
---|---|---|---|
vein endothelial cell | 4 studies | 34% ± 8% | |
endothelial cell | 4 studies | 19% ± 1% |
Insufficient scRNA-seq data for expression of CCL23 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 89% | 218.58 | 218 / 245 | 81% | 3.90 | 405 / 502 |
lung | 100% | 544.58 | 576 / 578 | 67% | 3.89 | 778 / 1155 |
uterus | 97% | 349.98 | 165 / 170 | 32% | 1.27 | 149 / 459 |
bladder | 86% | 122.81 | 18 / 21 | 41% | 1.71 | 208 / 504 |
breast | 92% | 175.37 | 423 / 459 | 32% | 0.78 | 353 / 1118 |
liver | 76% | 97.62 | 171 / 226 | 39% | 0.84 | 157 / 406 |
intestine | 74% | 113.07 | 714 / 966 | 40% | 1.28 | 213 / 527 |
kidney | 73% | 246.39 | 65 / 89 | 41% | 0.81 | 368 / 901 |
esophagus | 81% | 112.41 | 1167 / 1445 | 28% | 0.64 | 52 / 183 |
stomach | 64% | 62.11 | 231 / 359 | 45% | 1.86 | 128 / 286 |
thymus | 62% | 75.67 | 403 / 653 | 47% | 1.29 | 282 / 605 |
adrenal gland | 93% | 154.55 | 239 / 258 | 14% | 0.47 | 33 / 230 |
spleen | 100% | 345.07 | 240 / 241 | 0% | 0 | 0 / 0 |
adipose | 95% | 178.77 | 1139 / 1204 | 0% | 0 | 0 / 0 |
skin | 51% | 53.73 | 918 / 1809 | 36% | 1.16 | 170 / 472 |
pancreas | 13% | 6.20 | 44 / 328 | 71% | 4.60 | 127 / 178 |
lymph node | 0% | 0 | 0 / 0 | 83% | 3.29 | 24 / 29 |
ovary | 46% | 66.01 | 82 / 180 | 13% | 0.25 | 57 / 430 |
blood vessel | 54% | 68.30 | 723 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 36% | 0.81 | 16 / 45 |
peripheral blood | 21% | 22.14 | 198 / 929 | 0% | 0 | 0 / 0 |
heart | 8% | 5.07 | 70 / 861 | 0% | 0 | 0 / 0 |
muscle | 7% | 3.26 | 54 / 803 | 0% | 0 | 0 / 0 |
brain | 0% | 0 | 0 / 2642 | 5% | 0.22 | 37 / 705 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0006954 | Biological process | inflammatory response |
GO_0043547 | Biological process | positive regulation of GTPase activity |
GO_0007165 | Biological process | signal transduction |
GO_0006935 | Biological process | chemotaxis |
GO_0006874 | Biological process | intracellular calcium ion homeostasis |
GO_0007267 | Biological process | cell-cell signaling |
GO_0006955 | Biological process | immune response |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0070098 | Biological process | chemokine-mediated signaling pathway |
GO_0030335 | Biological process | positive regulation of cell migration |
GO_0048245 | Biological process | eosinophil chemotaxis |
GO_0061844 | Biological process | antimicrobial humoral immune response mediated by antimicrobial peptide |
GO_0002548 | Biological process | monocyte chemotaxis |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0008201 | Molecular function | heparin binding |
GO_0031726 | Molecular function | CCR1 chemokine receptor binding |
GO_0008009 | Molecular function | chemokine activity |
GO_0048020 | Molecular function | CCR chemokine receptor binding |
Gene name | CCL23 |
Protein name | C-C motif chemokine 23 (CK-beta-8) (CKB-8) (Macrophage inflammatory protein 3) (MIP-3) (Myeloid progenitor inhibitory factor 1) (MPIF-1) (Small-inducible cytokine A23) [Cleaved into: CCL23(19-99); CCL23(22-99); CCL23(27-99); CCL23(30-99)] C-C motif chemokine 23 (C-C motif chemokine ligand 23) |
Synonyms | MIP3 MPIF1 SCYA23 |
Description | FUNCTION: Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than CCL23. . |
Accessions | ENST00000615050.2 [P55773-2] P55773 ENST00000631414.1 ENST00000610342.2 ENST00000632633.1 ENST00000612516.4 [P55773-1] ENST00000613876.1 A0A087WV09 |