CCL22 | OmnibusX

Name	Number of supported studies	Average coverage
dendritic cell	7 studies	63% ± 17%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CCL22 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	86%	175.35	496 / 578	88%	13.43	1021 / 1155
breast	64%	104.05	296 / 459	82%	9.53	921 / 1118
esophagus	41%	87.80	597 / 1445	84%	7.44	153 / 183
bladder	48%	22.67	10 / 21	74%	9.53	372 / 504
intestine	41%	120.07	393 / 966	76%	6.33	398 / 527
skin	73%	302.48	1325 / 1809	40%	2.93	191 / 472
prostate	47%	29.26	115 / 245	57%	3.04	285 / 502
stomach	26%	24.75	93 / 359	76%	7.80	217 / 286
spleen	98%	180.15	235 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	15.42	42 / 45
lymph node	0%	0	0 / 0	86%	156.93	25 / 29
pancreas	4%	2.80	14 / 328	81%	10.71	145 / 178
thymus	24%	29.02	157 / 653	61%	5.80	370 / 605
uterus	8%	6.04	14 / 170	66%	7.71	304 / 459
kidney	20%	15.18	18 / 89	31%	1.29	281 / 901
adipose	42%	72.59	511 / 1204	0%	0	0 / 0
peripheral blood	30%	13527.34	280 / 929	0%	0	0 / 0
adrenal gland	20%	16.36	52 / 258	9%	3.23	21 / 230
ovary	6%	2.99	11 / 180	15%	0.68	65 / 430
liver	8%	4.59	17 / 226	10%	0.69	40 / 406
blood vessel	11%	18.37	153 / 1335	0%	0	0 / 0
brain	3%	2.24	89 / 2642	5%	0.36	33 / 705
heart	5%	3.40	46 / 861	0%	0	0 / 0
muscle	3%	1.16	21 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	1%	0.04	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007165	Biological process	signal transduction
GO_0009615	Biological process	response to virus
GO_0006955	Biological process	immune response
GO_0061844	Biological process	antimicrobial humoral immune response mediated by antimicrobial peptide
GO_0070098	Biological process	chemokine-mediated signaling pathway
GO_0030335	Biological process	positive regulation of cell migration
GO_0006954	Biological process	inflammatory response
GO_0006935	Biological process	chemotaxis
GO_0043547	Biological process	positive regulation of GTPase activity
GO_0007267	Biological process	cell-cell signaling
GO_0048245	Biological process	eosinophil chemotaxis
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0048020	Molecular function	CCR chemokine receptor binding
GO_0005515	Molecular function	protein binding
GO_0008009	Molecular function	chemokine activity

Gene name	CCL22
Protein name	C-C motif chemokine 22 (CC chemokine STCP-1) (MDC(1-69)) (Macrophage-derived chemokine) (Small-inducible cytokine A22) (Stimulated T-cell chemotactic protein 1) [Cleaved into: MDC(3-69); MDC(5-69); MDC(7-69)]
Synonyms	A-152E5.1 MDC SCYA22
Description	FUNCTION: May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.
Accessions	O00626 ENST00000219235.5

CCL22 report