CCL18 | OmnibusX

Name	Number of supported studies	Average coverage
macrophage	10 studies	32% ± 12%	Explore
alveolar macrophage	7 studies	42% ± 15%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CCL18 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	5638.86	576 / 578	89%	222.54	1031 / 1155
intestine	53%	337.10	515 / 966	55%	64.84	292 / 527
esophagus	51%	268.54	740 / 1445	56%	49.10	102 / 183
thymus	36%	133.85	238 / 653	61%	57.03	370 / 605
lymph node	0%	0	0 / 0	97%	553.67	28 / 29
spleen	89%	470.15	215 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	82%	150.35	37 / 45
skin	16%	41.04	290 / 1809	58%	54.19	272 / 472
pancreas	2%	1.90	5 / 328	72%	75.99	128 / 178
bladder	19%	76.71	4 / 21	53%	65.66	268 / 504
breast	46%	168.23	212 / 459	26%	17.98	288 / 1118
stomach	11%	18.25	40 / 359	58%	70.69	166 / 286
adipose	61%	428.67	732 / 1204	0%	0	0 / 0
kidney	6%	29.62	5 / 89	42%	66.31	375 / 901
uterus	2%	3.72	3 / 170	40%	40.15	182 / 459
blood vessel	37%	432.67	490 / 1335	0%	0	0 / 0
heart	32%	118.48	275 / 861	0%	0	0 / 0
liver	11%	19.91	24 / 226	15%	5.88	62 / 406
eye	0%	0	0 / 0	25%	11.47	20 / 80
prostate	7%	20.53	17 / 245	16%	5.56	80 / 502
ovary	8%	30.22	14 / 180	12%	7.80	52 / 430
adrenal gland	12%	21.81	32 / 258	7%	5.44	17 / 230
peripheral blood	12%	47.26	111 / 929	0%	0	0 / 0
brain	0%	3.75	13 / 2642	5%	11.97	36 / 705
muscle	2%	2.40	17 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007154	Biological process	cell communication
GO_0007165	Biological process	signal transduction
GO_0006955	Biological process	immune response
GO_0061844	Biological process	antimicrobial humoral immune response mediated by antimicrobial peptide
GO_0070098	Biological process	chemokine-mediated signaling pathway
GO_0006954	Biological process	inflammatory response
GO_0030335	Biological process	positive regulation of cell migration
GO_0006935	Biological process	chemotaxis
GO_0043547	Biological process	positive regulation of GTPase activity
GO_0007267	Biological process	cell-cell signaling
GO_0048245	Biological process	eosinophil chemotaxis
GO_0005615	Cellular component	extracellular space
GO_0048020	Molecular function	CCR chemokine receptor binding
GO_0005515	Molecular function	protein binding
GO_0008009	Molecular function	chemokine activity

Gene name	CCL18
Protein name	C-C motif chemokine 18 (Alternative macrophage activation-associated CC chemokine 1) (AMAC-1) (CC chemokine PARC) (Dendritic cell chemokine 1) (DC-CK1) (Macrophage inflammatory protein 4) (MIP-4) (Pulmonary and activation-regulated chemokine) (Small-inducible cytokine A18) [Cleaved into: CCL18(1-68); CCL18(3-69); CCL18(4-69)]
Synonyms	AMAC1 PARC DCCK1 MIP4 SCYA18
Description	FUNCTION: Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. .
Accessions	ENST00000616054.2 ENST00000615723.2 ENST00000614828.2 P55774

CCL18 report