Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 16 studies | 27% ± 11% | |
| endothelial cell | 14 studies | 27% ± 10% | |
| fibroblast | 11 studies | 21% ± 6% | |
| oligodendrocyte | 10 studies | 32% ± 13% | |
| glutamatergic neuron | 10 studies | 43% ± 25% | |
| regulatory T cell | 10 studies | 18% ± 4% | |
| CD4-positive, alpha-beta T cell | 8 studies | 21% ± 6% | |
| oligodendrocyte precursor cell | 8 studies | 32% ± 14% | |
| adipocyte | 8 studies | 24% ± 7% | |
| astrocyte | 8 studies | 32% ± 10% | |
| GABAergic neuron | 7 studies | 49% ± 19% | |
| T cell | 7 studies | 18% ± 3% | |
| naive thymus-derived CD4-positive, alpha-beta T cell | 6 studies | 22% ± 5% | |
| interneuron | 6 studies | 44% ± 23% | |
| macrophage | 6 studies | 26% ± 3% | |
| microglial cell | 6 studies | 25% ± 5% | |
| epithelial cell | 6 studies | 28% ± 6% | |
| retinal cone cell | 6 studies | 30% ± 9% | |
| retinal rod cell | 6 studies | 28% ± 7% | |
| CD8-positive, alpha-beta T cell | 5 studies | 19% ± 2% | |
| neuron | 5 studies | 34% ± 13% | |
| pericyte | 5 studies | 20% ± 4% | |
| retina horizontal cell | 5 studies | 21% ± 5% | |
| B cell | 4 studies | 19% ± 2% | |
| effector memory CD8-positive, alpha-beta T cell | 4 studies | 22% ± 4% | |
| retinal bipolar neuron | 4 studies | 23% ± 5% | |
| granule cell | 4 studies | 24% ± 9% | |
| smooth muscle cell | 4 studies | 19% ± 2% | |
| amacrine cell | 4 studies | 26% ± 5% | |
| cardiac muscle cell | 4 studies | 20% ± 2% | |
| lymphocyte | 4 studies | 25% ± 7% | |
| GABAergic interneuron | 3 studies | 27% ± 3% | |
| Mueller cell | 3 studies | 22% ± 5% | |
| glycinergic amacrine cell | 3 studies | 21% ± 4% | |
| natural killer cell | 3 studies | 16% ± 0% | |
| ependymal cell | 3 studies | 41% ± 12% | |
| endothelial cell of lymphatic vessel | 3 studies | 19% ± 3% | |
| basal cell | 3 studies | 25% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1024.44 | 1445 / 1445 | 100% | 3.88 | 183 / 183 |
| thymus | 100% | 1705.52 | 653 / 653 | 100% | 5.73 | 603 / 605 |
| breast | 100% | 1460.08 | 459 / 459 | 100% | 6.71 | 1114 / 1118 |
| prostate | 100% | 1456.60 | 245 / 245 | 99% | 4.25 | 498 / 502 |
| lung | 100% | 1127.16 | 578 / 578 | 99% | 3.90 | 1144 / 1155 |
| brain | 99% | 970.56 | 2620 / 2642 | 100% | 5.14 | 704 / 705 |
| bladder | 100% | 1305.00 | 21 / 21 | 99% | 3.71 | 497 / 504 |
| pancreas | 100% | 701.13 | 328 / 328 | 98% | 3.66 | 175 / 178 |
| uterus | 100% | 1696.14 | 170 / 170 | 98% | 4.33 | 451 / 459 |
| ovary | 100% | 1757.01 | 180 / 180 | 98% | 3.55 | 420 / 430 |
| intestine | 100% | 1313.67 | 966 / 966 | 96% | 3.65 | 508 / 527 |
| stomach | 100% | 943.27 | 359 / 359 | 96% | 3.67 | 274 / 286 |
| adrenal gland | 100% | 872.68 | 258 / 258 | 96% | 3.44 | 220 / 230 |
| kidney | 100% | 1005.45 | 89 / 89 | 94% | 3.11 | 847 / 901 |
| skin | 100% | 942.26 | 1808 / 1809 | 89% | 3.62 | 419 / 472 |
| liver | 98% | 427.93 | 221 / 226 | 73% | 1.58 | 297 / 406 |
| blood vessel | 100% | 1197.03 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1323.13 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.35 | 1 / 1 |
| adipose | 100% | 1164.10 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 99% | 773.00 | 798 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 3.42 | 44 / 45 |
| heart | 97% | 705.71 | 833 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 4.57 | 28 / 29 |
| peripheral blood | 56% | 319.00 | 523 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 54% | 1.50 | 43 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0060271 | Biological process | cilium assembly |
| GO_0001895 | Biological process | retina homeostasis |
| GO_1903564 | Biological process | regulation of protein localization to cilium |
| GO_0050908 | Biological process | detection of light stimulus involved in visual perception |
| GO_0001578 | Biological process | microtubule bundle formation |
| GO_0034451 | Cellular component | centriolar satellite |
| GO_0005874 | Cellular component | microtubule |
| GO_0001750 | Cellular component | photoreceptor outer segment |
| GO_0005813 | Cellular component | centrosome |
| GO_0001917 | Cellular component | photoreceptor inner segment |
| GO_0090543 | Cellular component | Flemming body |
| GO_0005929 | Cellular component | cilium |
| GO_0005829 | Cellular component | cytosol |
| GO_0035869 | Cellular component | ciliary transition zone |
| GO_0030054 | Cellular component | cell junction |
| GO_0036064 | Cellular component | ciliary basal body |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0008017 | Molecular function | microtubule binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CCDC66 |
| Protein name | Coiled-coil domain-containing protein 66 Coiled-coil domain containing 66 |
| Synonyms | |
| Description | FUNCTION: Microtubule-binding protein required for ciliogenesis . May function in ciliogenesis by mediating the transport of proteins like BBS4 to the cilium, but also through the organization of the centriolar satellites . Plays a role in retina morphogenesis and/or homeostasis (By similarity). . |
| Accessions | ENST00000422222.5 ENST00000326595.11 [A2RUB6-3] F8WB87 ENST00000422788.5 ENST00000341455.10 ENST00000471681.5 F2Z2K6 ENST00000439445.5 F8WDJ0 ENST00000434467.5 F8WCY0 ENST00000394672.8 [A2RUB6-1] A2RUB6 C9JYB8 |