Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 20 studies | 31% ± 14% | |
pericyte | 18 studies | 28% ± 13% | |
oligodendrocyte | 16 studies | 42% ± 16% | |
smooth muscle cell | 11 studies | 30% ± 15% | |
astrocyte | 10 studies | 24% ± 6% | |
glutamatergic neuron | 10 studies | 61% ± 17% | |
epithelial cell | 8 studies | 41% ± 18% | |
goblet cell | 8 studies | 50% ± 15% | |
GABAergic neuron | 8 studies | 48% ± 19% | |
endothelial cell | 7 studies | 33% ± 14% | |
neuron | 6 studies | 48% ± 18% | |
connective tissue cell | 6 studies | 28% ± 11% | |
oligodendrocyte precursor cell | 6 studies | 23% ± 8% | |
interneuron | 6 studies | 46% ± 18% | |
abnormal cell | 5 studies | 32% ± 9% | |
enterocyte | 5 studies | 29% ± 11% | |
amacrine cell | 5 studies | 34% ± 12% | |
squamous epithelial cell | 4 studies | 30% ± 9% | |
pancreatic A cell | 4 studies | 55% ± 21% | |
type B pancreatic cell | 4 studies | 52% ± 23% | |
retinal ganglion cell | 4 studies | 53% ± 20% | |
brush cell | 4 studies | 27% ± 5% | |
microglial cell | 4 studies | 17% ± 1% | |
pancreatic D cell | 3 studies | 51% ± 18% | |
intestinal crypt stem cell | 3 studies | 25% ± 12% | |
transit amplifying cell | 3 studies | 42% ± 17% | |
retinal bipolar neuron | 3 studies | 43% ± 13% | |
kidney loop of Henle epithelial cell | 3 studies | 26% ± 1% | |
renal alpha-intercalated cell | 3 studies | 60% ± 18% | |
renal principal cell | 3 studies | 57% ± 11% | |
ON-bipolar cell | 3 studies | 34% ± 14% | |
rod bipolar cell | 3 studies | 38% ± 18% | |
myofibroblast cell | 3 studies | 28% ± 12% | |
luminal hormone-sensing cell of mammary gland | 3 studies | 23% ± 6% | |
enteroendocrine cell | 3 studies | 46% ± 15% | |
granule cell | 3 studies | 24% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 27159.13 | 2636 / 2642 | 99% | 250.71 | 701 / 705 |
intestine | 98% | 7166.07 | 949 / 966 | 97% | 165.02 | 513 / 527 |
kidney | 100% | 8369.33 | 89 / 89 | 95% | 133.20 | 859 / 901 |
liver | 96% | 3138.06 | 218 / 226 | 97% | 98.97 | 392 / 406 |
adrenal gland | 97% | 4230.18 | 251 / 258 | 95% | 226.24 | 218 / 230 |
prostate | 97% | 4290.10 | 238 / 245 | 88% | 99.96 | 442 / 502 |
bladder | 90% | 2976.00 | 19 / 21 | 84% | 172.75 | 425 / 504 |
esophagus | 84% | 3470.83 | 1220 / 1445 | 75% | 115.89 | 138 / 183 |
breast | 72% | 2004.28 | 330 / 459 | 84% | 109.66 | 937 / 1118 |
uterus | 92% | 3220.52 | 157 / 170 | 56% | 68.25 | 258 / 459 |
lung | 99% | 7730.47 | 572 / 578 | 49% | 49.99 | 563 / 1155 |
stomach | 38% | 1498.23 | 137 / 359 | 93% | 165.36 | 266 / 286 |
ovary | 96% | 3209.42 | 173 / 180 | 26% | 18.09 | 111 / 430 |
thymus | 33% | 667.69 | 213 / 653 | 74% | 182.36 | 446 / 605 |
pancreas | 3% | 61.51 | 9 / 328 | 98% | 204.92 | 175 / 178 |
skin | 51% | 2361.05 | 916 / 1809 | 47% | 35.14 | 222 / 472 |
adipose | 61% | 1460.87 | 736 / 1204 | 0% | 0 | 0 / 0 |
heart | 43% | 943.08 | 374 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 34% | 13.93 | 27 / 80 |
spleen | 34% | 794.21 | 81 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 30% | 646.43 | 400 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 18% | 11.10 | 8 / 45 |
muscle | 0% | 7.89 | 4 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 2.03 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050729 | Biological process | positive regulation of inflammatory response |
GO_0006469 | Biological process | negative regulation of protein kinase activity |
GO_0007616 | Biological process | long-term memory |
GO_0005575 | Cellular component | cellular_component |
GO_0045202 | Cellular component | synapse |
GO_0014069 | Cellular component | postsynaptic density |
GO_0030425 | Cellular component | dendrite |
GO_0019901 | Molecular function | protein kinase binding |
GO_0008427 | Molecular function | calcium-dependent protein kinase inhibitor activity |
Gene name | CAMK2N1 |
Protein name | Calcium/calmodulin-dependent protein kinase II inhibitor 1 (CaMKII inhibitory protein alpha) (CaMKIIN-alpha) CAMK2N1 protein |
Synonyms | |
Description | FUNCTION: Potent and specific inhibitor of CaM-kinase II (CAMK2) (By similarity). Plays a role in the maintenance of long-term retrieval-induced memory in response to contextual fear (By similarity). Modulates blood pressure and vascular reactivity via regulation of CAMK2 activity in addition to regulation of left ventricular mass (By similarity). Mediates the NLRP3 inflammasome in cardiomyocytes via acting as an inhibitor of the MAPK14/p38 and MAPK8/JNK pathways, thereby regulating ventricular remodeling and cardiac rhythm post-myocardial infarction (By similarity). Negatively effects insulin sensitivity and promotes lipid formation in adipose tissues independent of CAMK2 signaling (By similarity). . |
Accessions | ENST00000375078.4 Q7L2B8 Q7Z7J9 |