Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 15 studies | 36% ± 16% | |
endothelial cell | 13 studies | 27% ± 10% | |
platelet | 9 studies | 34% ± 8% | |
epithelial cell | 9 studies | 33% ± 14% | |
type II pneumocyte | 8 studies | 36% ± 15% | |
epithelial cell of proximal tubule | 7 studies | 39% ± 10% | |
astrocyte | 7 studies | 27% ± 10% | |
kidney loop of Henle epithelial cell | 6 studies | 25% ± 5% | |
retinal cone cell | 6 studies | 51% ± 23% | |
erythrocyte | 6 studies | 41% ± 23% | |
renal alpha-intercalated cell | 5 studies | 73% ± 4% | |
pericyte | 5 studies | 38% ± 18% | |
erythroblast | 5 studies | 29% ± 13% | |
kidney distal convoluted tubule epithelial cell | 4 studies | 68% ± 26% | |
goblet cell | 4 studies | 25% ± 9% | |
transit amplifying cell | 4 studies | 28% ± 11% | |
Mueller cell | 4 studies | 74% ± 20% | |
kidney connecting tubule epithelial cell | 3 studies | 86% ± 5% | |
progenitor cell | 3 studies | 54% ± 30% | |
renal principal cell | 3 studies | 78% ± 10% | |
megakaryocyte | 3 studies | 41% ± 17% | |
enterocyte | 3 studies | 46% ± 28% | |
GABAergic neuron | 3 studies | 17% ± 0% | |
hepatocyte | 3 studies | 28% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 11166.61 | 89 / 89 | 96% | 267.11 | 864 / 901 |
brain | 96% | 4058.29 | 2539 / 2642 | 95% | 163.64 | 668 / 705 |
liver | 100% | 4191.64 | 226 / 226 | 78% | 83.94 | 317 / 406 |
pancreas | 90% | 1184.38 | 296 / 328 | 75% | 84.02 | 133 / 178 |
stomach | 94% | 19096.43 | 337 / 359 | 69% | 183.72 | 197 / 286 |
lung | 87% | 1501.75 | 501 / 578 | 48% | 68.74 | 551 / 1155 |
intestine | 44% | 9452.46 | 424 / 966 | 68% | 115.19 | 357 / 527 |
thymus | 76% | 1303.36 | 494 / 653 | 29% | 15.81 | 177 / 605 |
esophagus | 32% | 523.43 | 468 / 1445 | 70% | 178.02 | 128 / 183 |
muscle | 97% | 1679.99 | 780 / 803 | 0% | 0 | 0 / 0 |
breast | 35% | 476.82 | 159 / 459 | 58% | 136.80 | 643 / 1118 |
skin | 69% | 1505.94 | 1248 / 1809 | 11% | 6.50 | 53 / 472 |
adrenal gland | 47% | 584.63 | 120 / 258 | 31% | 31.51 | 72 / 230 |
heart | 63% | 694.95 | 546 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 63% | 1082.99 | 582 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 62% | 68.27 | 28 / 45 |
uterus | 1% | 3.46 | 1 / 170 | 53% | 89.18 | 244 / 459 |
bladder | 0% | 0 | 0 / 21 | 41% | 50.89 | 207 / 504 |
spleen | 36% | 473.16 | 87 / 241 | 0% | 0 | 0 / 0 |
adipose | 24% | 201.02 | 284 / 1204 | 0% | 0 | 0 / 0 |
ovary | 0% | 0 | 0 / 180 | 17% | 7.77 | 75 / 430 |
lymph node | 0% | 0 | 0 / 0 | 14% | 4.57 | 4 / 29 |
prostate | 2% | 42.99 | 5 / 245 | 3% | 1.05 | 14 / 502 |
blood vessel | 4% | 41.23 | 57 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 4% | 3.50 | 3 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0044070 | Biological process | regulation of monoatomic anion transport |
GO_0002009 | Biological process | morphogenesis of an epithelium |
GO_0015670 | Biological process | carbon dioxide transport |
GO_0032849 | Biological process | positive regulation of cellular pH reduction |
GO_0006730 | Biological process | one-carbon metabolic process |
GO_0046903 | Biological process | secretion |
GO_0070050 | Biological process | neuron cellular homeostasis |
GO_2001150 | Biological process | positive regulation of dipeptide transmembrane transport |
GO_0038166 | Biological process | angiotensin-activated signaling pathway |
GO_0051453 | Biological process | regulation of intracellular pH |
GO_0032230 | Biological process | positive regulation of synaptic transmission, GABAergic |
GO_2001225 | Biological process | regulation of chloride transport |
GO_0043209 | Cellular component | myelin sheath |
GO_0005886 | Cellular component | plasma membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0045177 | Cellular component | apical part of cell |
GO_0004089 | Molecular function | carbonate dehydratase activity |
GO_0008270 | Molecular function | zinc ion binding |
GO_0004064 | Molecular function | arylesterase activity |
GO_0018820 | Molecular function | cyanamide hydratase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | CA2 |
Protein name | Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II) (Cyanamide hydratase CA2) (EC 4.2.1.69) Carbonic anhydrase 2 |
Synonyms | |
Description | FUNCTION: Catalyzes the reversible hydration of carbon dioxide . Can also hydrate cyanamide to urea . Stimulates the chloride-bicarbonate exchange activity of SLC26A6 . Essential for bone resorption and osteoclast differentiation . Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. . |
Accessions | E5RK37 ENST00000520127.5 ENST00000285379.10 E5RID5 ENST00000522742.1 P00918 |