BRD1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1903706Biological processregulation of hemopoiesis
GO_0043249Biological processerythrocyte maturation
GO_0051602Biological processresponse to electrical stimulus
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0035902Biological processresponse to immobilization stress
GO_0006338Biological processchromatin remodeling
GO_0006355Biological processregulation of DNA-templated transcription
GO_0045648Biological processpositive regulation of erythrocyte differentiation
GO_0050793Biological processregulation of developmental process
GO_0016607Cellular componentnuclear speck
GO_0043204Cellular componentperikaryon
GO_0030425Cellular componentdendrite
GO_0036409Cellular componenthistone H3-K14 acetyltransferase complex
GO_0070776Cellular componentMOZ/MORF histone acetyltransferase complex
GO_0005634Cellular componentnucleus
GO_0043997Molecular functionhistone H4K12 acetyltransferase activity
GO_0036408Molecular functionhistone H3K14 acetyltransferase activity
GO_0042393Molecular functionhistone binding
GO_0043996Molecular functionhistone H4K8 acetyltransferase activity
GO_0140566Molecular functionhistone reader activity
GO_0043995Molecular functionhistone H4K5 acetyltransferase activity
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameBRD1
Protein nameBromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2)
BRD1 protein
Bromodomain containing 1
SynonymsBRPF2
BRL
DescriptionFUNCTION: Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, that acts as a regulator of hematopoiesis . Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac), thereby promoting erythroid differentiation . .

AccessionsENST00000438393.5
ENST00000404034.5 [O95696-1]
ENST00000404760.6 [O95696-2]
J3KQ61
O95696
Q86X06
ENST00000457780.3 [O95696-2]
ENST00000216267.12 [O95696-1]