ATP8B4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007030Biological processGolgi organization
GO_0045332Biological processphospholipid translocation
GO_0005802Cellular componenttrans-Golgi network
GO_1990531Cellular componentphospholipid-translocating ATPase complex
GO_0070821Cellular componenttertiary granule membrane
GO_0005794Cellular componentGolgi apparatus
GO_0035579Cellular componentspecific granule membrane
GO_0005886Cellular componentplasma membrane
GO_0005524Molecular functionATP binding
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity
GO_0000287Molecular functionmagnesium ion binding
GO_0140326Molecular functionATPase-coupled intramembrane lipid transporter activity

IV. Literature review

[source]
Gene nameATP8B4
Protein nameATP8B4 protein
ATPase phospholipid transporting 8B4 (putative)
Phospholipid-transporting ATPase (EC 7.6.2.1)
Probable phospholipid-transporting ATPase IM (EC 7.6.2.1) (ATPase class I type 8B member 4) (P4-ATPase flippase complex alpha subunit ATP8B4)
SynonymsKIAA1939
DescriptionFUNCTION: Component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). .

AccessionsENST00000557955.5
ENST00000558024.1
A0A6I8PRR9
H0YMB5
H0YLC1
ENST00000674213.1
ENST00000558959.5
ENST00000559829.5
ENST00000559726.5
H0YMP8
A0A6I8PS08
Q6PG43
ENST00000558458.1
ENST00000284509.11
ENST00000558906.5
ENST00000558829.1
H0YM66
Q8TF62
H0YLJ1