ATG10 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000422Biological processautophagy of mitochondrion
GO_0015031Biological processprotein transport
GO_0006914Biological processautophagy
GO_0006983Biological processER overload response
GO_0032446Biological processprotein modification by small protein conjugation
GO_0031401Biological processpositive regulation of protein modification process
GO_0000045Biological processautophagosome assembly
GO_0006497Biological processprotein lipidation
GO_0005829Cellular componentcytosol
GO_0019777Molecular functionAtg12 transferase activity
GO_0005515Molecular functionprotein binding
GO_0061651Molecular functionAtg12 conjugating enzyme activity

IV. Literature review

[source]
Gene nameATG10
Protein nameAutophagy related 10
Ubiquitin-like-conjugating enzyme ATG10 (EC 2.3.2.-) (Autophagy-related protein 10) (APG10-like)
Ubiquitin-like-conjugating enzyme ATG10 (Autophagy-related protein 10)
SynonymsPP12616
APG10L
DescriptionFUNCTION: E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis. .

AccessionsENST00000504770.5
D6RBD1
ENST00000355178.8 [Q9H0Y0-2]
D6RC89
ENST00000513634.1
ENST00000513443.5 [Q9H0Y0-2]
Q9H0Y0
ENST00000510085.1
ENST00000282185.8 [Q9H0Y0-1]
ENST00000458350.7 [Q9H0Y0-1]
D6RDX3