ARHGAP32 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051056Biological processregulation of small GTPase mediated signal transduction
GO_0007264Biological processsmall GTPase-mediated signal transduction
GO_0010008Cellular componentendosome membrane
GO_0000139Cellular componentGolgi membrane
GO_0015629Cellular componentactin cytoskeleton
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005938Cellular componentcell cortex
GO_0005794Cellular componentGolgi apparatus
GO_0014069Cellular componentpostsynaptic density
GO_0043197Cellular componentdendritic spine
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0001650Cellular componentfibrillar center
GO_1901981Molecular functionphosphatidylinositol phosphate binding
GO_0005515Molecular functionprotein binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameARHGAP32
Protein nameARHGAP32
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)
Rho GTPase activating protein 32 (Rho GTPase-activating protein, isoform CRA_b)
Rho GTPase activating protein 32
SynonymshCG_2042955
GRIT
RICS
KIAA0712
DescriptionFUNCTION: GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity (By similarity). .

AccessionsA0A2X0SFD0
ENST00000525234.1
ENST00000527272.1 [A7KAX9-2]
A7KAX9
ENST00000392657.7 [A7KAX9-2]
ENST00000310343.13 [A7KAX9-1]
G3V174
E9PRH3
A0A804HK06
ENST00000524655.5
ENST00000682385.1