Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 39 studies | 44% ± 19% | |
mast cell | 29 studies | 54% ± 16% | |
endothelial cell | 24 studies | 29% ± 12% | |
ciliated cell | 19 studies | 61% ± 14% | |
myeloid cell | 14 studies | 44% ± 15% | |
capillary endothelial cell | 13 studies | 34% ± 19% | |
monocyte | 10 studies | 35% ± 15% | |
dendritic cell | 9 studies | 32% ± 8% | |
platelet | 9 studies | 38% ± 14% | |
epithelial cell | 9 studies | 31% ± 14% | |
microglial cell | 9 studies | 24% ± 8% | |
conventional dendritic cell | 9 studies | 26% ± 7% | |
alveolar macrophage | 8 studies | 53% ± 13% | |
plasmacytoid dendritic cell | 8 studies | 26% ± 9% | |
renal alpha-intercalated cell | 7 studies | 74% ± 11% | |
endothelial cell of lymphatic vessel | 6 studies | 21% ± 4% | |
mononuclear phagocyte | 6 studies | 30% ± 10% | |
kidney loop of Henle epithelial cell | 6 studies | 22% ± 7% | |
ionocyte | 5 studies | 62% ± 9% | |
vein endothelial cell | 5 studies | 27% ± 7% | |
pericyte | 5 studies | 21% ± 4% | |
mesothelial cell | 5 studies | 38% ± 17% | |
endothelial cell of vascular tree | 5 studies | 20% ± 3% | |
megakaryocyte | 4 studies | 58% ± 24% | |
classical monocyte | 4 studies | 29% ± 11% | |
lymphocyte | 4 studies | 22% ± 5% | |
basal cell | 4 studies | 28% ± 10% | |
GABAergic neuron | 4 studies | 29% ± 7% | |
glutamatergic neuron | 4 studies | 30% ± 9% | |
leukocyte | 4 studies | 20% ± 2% | |
natural killer cell | 3 studies | 17% ± 2% | |
placental villous trophoblast | 3 studies | 23% ± 5% | |
plasma cell | 3 studies | 22% ± 7% | |
retinal pigment epithelial cell | 3 studies | 24% ± 6% | |
tissue-resident macrophage | 3 studies | 45% ± 9% | |
secretory cell | 3 studies | 32% ± 7% | |
abnormal cell | 3 studies | 21% ± 5% | |
granulocyte | 3 studies | 45% ± 8% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 28% ± 13% | |
type I pneumocyte | 3 studies | 18% ± 2% | |
transit amplifying cell | 3 studies | 24% ± 12% | |
interneuron | 3 studies | 30% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 2458.23 | 328 / 328 | 100% | 32.97 | 178 / 178 |
breast | 100% | 1727.84 | 459 / 459 | 99% | 30.18 | 1112 / 1118 |
prostate | 100% | 1376.10 | 244 / 245 | 99% | 28.28 | 498 / 502 |
kidney | 100% | 2632.38 | 89 / 89 | 99% | 46.00 | 888 / 901 |
thymus | 100% | 1935.71 | 653 / 653 | 98% | 51.05 | 595 / 605 |
lung | 100% | 4085.01 | 578 / 578 | 98% | 30.21 | 1131 / 1155 |
stomach | 99% | 2415.55 | 354 / 359 | 99% | 35.92 | 283 / 286 |
intestine | 97% | 1261.63 | 938 / 966 | 99% | 37.56 | 520 / 527 |
adrenal gland | 100% | 5719.77 | 258 / 258 | 94% | 28.96 | 216 / 230 |
skin | 98% | 2301.80 | 1769 / 1809 | 90% | 28.58 | 427 / 472 |
uterus | 96% | 842.79 | 164 / 170 | 90% | 15.22 | 415 / 459 |
bladder | 90% | 905.33 | 19 / 21 | 94% | 23.23 | 474 / 504 |
esophagus | 86% | 553.04 | 1241 / 1445 | 93% | 22.75 | 170 / 183 |
ovary | 85% | 888.14 | 153 / 180 | 86% | 12.26 | 368 / 430 |
brain | 38% | 252.08 | 1009 / 2642 | 66% | 11.82 | 462 / 705 |
adipose | 100% | 2622.88 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 1124.69 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 93% | 1101.19 | 1237 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 90% | 15.84 | 26 / 29 |
tonsil | 0% | 0 | 0 / 0 | 82% | 11.71 | 37 / 45 |
muscle | 75% | 477.21 | 602 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 72% | 1155.62 | 673 / 929 | 0% | 0 | 0 / 0 |
liver | 23% | 114.28 | 53 / 226 | 47% | 6.46 | 192 / 406 |
heart | 65% | 387.29 | 558 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 28% | 3.17 | 22 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0008360 | Biological process | regulation of cell shape |
GO_2000145 | Biological process | regulation of cell motility |
GO_0030833 | Biological process | regulation of actin filament polymerization |
GO_0007264 | Biological process | small GTPase-mediated signal transduction |
GO_0032956 | Biological process | regulation of actin cytoskeleton organization |
GO_0001726 | Cellular component | ruffle |
GO_0016607 | Cellular component | nuclear speck |
GO_0005829 | Cellular component | cytosol |
GO_0005881 | Cellular component | cytoplasmic microtubule |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0045296 | Molecular function | cadherin binding |
GO_0005096 | Molecular function | GTPase activator activity |
Gene name | ARHGAP18 |
Protein name | Rho GTPase-activating protein 18 (MacGAP) (Rho-type GTPase-activating protein 18) |
Synonyms | |
Description | FUNCTION: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state . Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 . Regulates cell shape, spreading, and migration . . |
Accessions | Q8N392 ENST00000368149.3 [Q8N392-1] |