ARCN1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008344Biological processadult locomotory behavior
GO_0006886Biological processintracellular protein transport
GO_0006888Biological processendoplasmic reticulum to Golgi vesicle-mediated transport
GO_0006890Biological processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO_0043473Biological processpigmentation
GO_0021691Biological processcerebellar Purkinje cell layer maturation
GO_0051645Biological processGolgi localization
GO_0000139Cellular componentGolgi membrane
GO_0030126Cellular componentCOPI vesicle coat
GO_0005829Cellular componentcytosol
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0030133Cellular componenttransport vesicle
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameARCN1
Protein nameCoatomer subunit delta
Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP)
SynonymshCG_40220
COPD
DescriptionFUNCTION: Component of the coatomer, a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). .

FUNCTION: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. .

FUNCTION: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. .

FUNCTION: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. .

FUNCTION: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. .

AccessionsQ6P1Q5
ENST00000264028.5 [P48444-1]
P48444
ENST00000359415.8
ENST00000392859.7 [P48444-2]
B0YIW6
E9PK34
B0YIW5
ENST00000534182.2