APEH report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006508Biological processproteolysis
GO_0006415Biological processtranslational termination
GO_0050435Biological processamyloid-beta metabolic process
GO_1904813Cellular componentficolin-1-rich granule lumen
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0005576Cellular componentextracellular region
GO_0031965Cellular componentnuclear membrane
GO_0004252Molecular functionserine-type endopeptidase activity
GO_0005515Molecular functionprotein binding
GO_0042802Molecular functionidentical protein binding
GO_0008242Molecular functionomega peptidase activity
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameAPEH
Protein nameAcylaminoacyl-peptide hydrolase
Acylamino-acid-releasing enzyme (EC 3.4.19.1) (Acyl-peptide hydrolase) (Acylaminoacyl-peptidase)
Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH)
SynonymsD3S48E
D3F15S2
DNF15S2
DescriptionFUNCTION: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus . It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser (By similarity). Also, involved in the degradation of oxidized and glycated proteins . .

AccessionsH0YFE5
ENST00000442186.5
H7C393
P13798
F8WEH5
ENST00000296456.10
ENST00000457042.1
F8WBC4
ENST00000447436.5
ENST00000447541.5
ENST00000449966.5
C9JIF9
ENST00000446089.5
ENST00000438011.5
ENST00000469362.6
C9JLK2
H7C273
H7C1U0