ANTXR1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030036Biological processactin cytoskeleton organization
GO_1901202Biological processnegative regulation of extracellular matrix assembly
GO_0034446Biological processsubstrate adhesion-dependent cell spreading
GO_0022414Biological processreproductive process
GO_0001568Biological processblood vessel development
GO_0009986Cellular componentcell surface
GO_0010008Cellular componentendosome membrane
GO_0031527Cellular componentfilopodium membrane
GO_0031258Cellular componentlamellipodium membrane
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0004888Molecular functiontransmembrane signaling receptor activity
GO_0051015Molecular functionactin filament binding
GO_0005518Molecular functioncollagen binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameANTXR1
Protein nameAnthrax toxin receptor 1 (Tumor endothelial marker 8)
ANTXR cell adhesion molecule 1
ANTXR1 protein
SynonymsTEM8
ATR
DescriptionFUNCTION: Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. .; FUNCTION: (Microbial infection) Acts as a receptor for protective antigen (PA) of B.anthracis. .

AccessionsA0A7P0T9B0
ENST00000409829.7 [Q9H6X2-4]
ENST00000679548.1
ENST00000463335.2 [Q9H6X2-3]
ENST00000303714.9 [Q9H6X2-1]
H0YC24
ENST00000409349.7 [Q9H6X2-2]
Q9H6X2
ENST00000681816.1
A0A7P0Z463
Q96EC6
ENST00000482235.2