ANGPT4 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of ANGPT4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	95%	444.56	621 / 653	35%	1.11	213 / 605
uterus	98%	860.99	167 / 170	6%	0.20	27 / 459
breast	98%	1584.88	452 / 459	5%	0.10	58 / 1118
ovary	96%	891.97	172 / 180	4%	0.16	19 / 430
adipose	98%	1392.11	1181 / 1204	0%	0	0 / 0
bladder	76%	232.90	16 / 21	8%	0.85	38 / 504
blood vessel	80%	482.86	1062 / 1335	0%	0	0 / 0
skin	64%	224.02	1149 / 1809	0%	0.01	2 / 472
prostate	55%	113.20	135 / 245	2%	0.02	8 / 502
lung	51%	89.72	292 / 578	3%	0.07	40 / 1155
adrenal gland	28%	44.93	71 / 258	21%	0.37	49 / 230
kidney	11%	12.80	10 / 89	23%	0.51	204 / 901
stomach	31%	55.91	110 / 359	1%	0.02	4 / 286
esophagus	23%	47.38	336 / 1445	3%	0.06	5 / 183
brain	8%	10.13	199 / 2642	18%	0.37	128 / 705
intestine	20%	42.77	195 / 966	0%	0.01	2 / 527
pancreas	5%	5.86	16 / 328	8%	0.16	14 / 178
liver	6%	6.63	13 / 226	3%	0.15	11 / 406
heart	8%	11.85	68 / 861	0%	0	0 / 0
muscle	3%	3.65	24 / 803	0%	0	0 / 0
spleen	2%	1.85	4 / 241	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007165	Biological process	signal transduction
GO_0010595	Biological process	positive regulation of endothelial cell migration
GO_0043536	Biological process	positive regulation of blood vessel endothelial cell migration
GO_0071456	Biological process	cellular response to hypoxia
GO_0001525	Biological process	angiogenesis
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0050731	Biological process	positive regulation of peptidyl-tyrosine phosphorylation
GO_0007219	Biological process	Notch signaling pathway
GO_0001935	Biological process	endothelial cell proliferation
GO_0045766	Biological process	positive regulation of angiogenesis
GO_0043537	Biological process	negative regulation of blood vessel endothelial cell migration
GO_0016525	Biological process	negative regulation of angiogenesis
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0030297	Molecular function	transmembrane receptor protein tyrosine kinase activator activity
GO_0030971	Molecular function	receptor tyrosine kinase binding

Gene name	ANGPT4
Protein name	Angiopoietin-4 (ANG-4) (Angiopoietin-3) (ANG-3)
Synonyms	ANG4 ANG3
Description	FUNCTION: Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis. .
Accessions	ENST00000381922.5 [Q9Y264-1] Q9Y264

ANGPT4 report