AMIGO1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AMIGO1 at tissue level.

III. Associated gene sets

GO_1901381Biological processpositive regulation of potassium ion transmembrane transport
GO_0050772Biological processpositive regulation of axonogenesis
GO_0042552Biological processmyelination
GO_0010976Biological processpositive regulation of neuron projection development
GO_0007409Biological processaxonogenesis
GO_0007413Biological processaxonal fasciculation
GO_0007156Biological processhomophilic cell adhesion via plasma membrane adhesion molecules
GO_0007420Biological processbrain development
GO_1905232Biological processcellular response to L-glutamate
GO_0051965Biological processpositive regulation of synapse assembly
GO_0007157Biological processheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO_0016020Cellular componentmembrane
GO_0043204Cellular componentperikaryon
GO_0032809Cellular componentneuronal cell body membrane
GO_0030425Cellular componentdendrite
GO_1990030Cellular componentpericellular basket
GO_0008076Cellular componentvoltage-gated potassium channel complex
GO_0015459Molecular functionpotassium channel regulator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAMIGO1
Protein nameAmphoterin-induced protein 1 (AMIGO-1) (Alivin-2)
SynonymsAMIGO
ALI2
KIAA1163
DescriptionFUNCTION: Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. .

AccessionsENST00000369862.1
ENST00000369864.5
Q86WK6