Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 14 studies | 28% ± 12% | |
macrophage | 14 studies | 34% ± 17% | |
microglial cell | 11 studies | 36% ± 13% | |
astrocyte | 10 studies | 38% ± 14% | |
oligodendrocyte | 10 studies | 28% ± 10% | |
glutamatergic neuron | 8 studies | 38% ± 25% | |
oligodendrocyte precursor cell | 8 studies | 27% ± 12% | |
myeloid cell | 7 studies | 28% ± 12% | |
adipocyte | 7 studies | 23% ± 5% | |
GABAergic neuron | 7 studies | 35% ± 20% | |
dendritic cell | 6 studies | 21% ± 2% | |
fibroblast | 6 studies | 24% ± 7% | |
interneuron | 5 studies | 36% ± 21% | |
epithelial cell | 5 studies | 30% ± 11% | |
cardiac muscle cell | 4 studies | 19% ± 1% | |
ciliated cell | 4 studies | 21% ± 6% | |
endothelial cell of lymphatic vessel | 4 studies | 24% ± 1% | |
monocyte | 4 studies | 32% ± 9% | |
pericyte | 4 studies | 23% ± 8% | |
smooth muscle cell | 4 studies | 19% ± 3% | |
type I pneumocyte | 4 studies | 25% ± 8% | |
classical monocyte | 3 studies | 21% ± 3% | |
non-classical monocyte | 3 studies | 22% ± 4% | |
neuron | 3 studies | 31% ± 14% | |
mononuclear phagocyte | 3 studies | 25% ± 1% | |
ependymal cell | 3 studies | 29% ± 13% | |
T cell | 3 studies | 21% ± 3% | |
alveolar macrophage | 3 studies | 31% ± 10% | |
type II pneumocyte | 3 studies | 21% ± 7% | |
lymphocyte | 3 studies | 29% ± 6% | |
basal cell | 3 studies | 30% ± 18% | |
goblet cell | 3 studies | 31% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1652.49 | 2639 / 2642 | 100% | 24.77 | 705 / 705 |
lung | 100% | 2017.30 | 578 / 578 | 100% | 19.33 | 1153 / 1155 |
prostate | 100% | 2052.24 | 245 / 245 | 100% | 19.29 | 501 / 502 |
breast | 100% | 2125.42 | 459 / 459 | 100% | 24.24 | 1114 / 1118 |
ovary | 100% | 2014.29 | 180 / 180 | 100% | 13.39 | 428 / 430 |
esophagus | 100% | 1910.06 | 1445 / 1445 | 99% | 19.70 | 182 / 183 |
bladder | 100% | 2133.29 | 21 / 21 | 99% | 16.33 | 501 / 504 |
stomach | 100% | 1698.15 | 359 / 359 | 99% | 15.12 | 284 / 286 |
intestine | 100% | 2024.70 | 966 / 966 | 99% | 14.11 | 522 / 527 |
thymus | 100% | 2262.89 | 653 / 653 | 99% | 21.86 | 599 / 605 |
uterus | 100% | 2176.29 | 170 / 170 | 99% | 18.68 | 454 / 459 |
kidney | 100% | 1513.87 | 89 / 89 | 99% | 21.98 | 891 / 901 |
pancreas | 100% | 926.09 | 327 / 328 | 98% | 16.42 | 175 / 178 |
adrenal gland | 100% | 2271.75 | 258 / 258 | 97% | 13.77 | 223 / 230 |
skin | 100% | 1972.41 | 1809 / 1809 | 93% | 16.29 | 440 / 472 |
liver | 100% | 841.11 | 226 / 226 | 70% | 6.24 | 283 / 406 |
adipose | 100% | 2153.99 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2047.38 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 2882.79 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 18.55 | 45 / 45 |
muscle | 99% | 774.86 | 793 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 920.62 | 843 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 97% | 1721.94 | 900 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 16.88 | 28 / 29 |
eye | 0% | 0 | 0 / 0 | 70% | 7.16 | 56 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007165 | Biological process | signal transduction |
GO_0008104 | Biological process | protein localization |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0051018 | Molecular function | protein kinase A binding |
GO_0005515 | Molecular function | protein binding |
Gene name | AKAP10 |
Protein name | A kinase anchor protein 10 isoform 2 A kinase anchor protein 10 isoform 1 A kinase anchor protein 10 isoform 4 A-kinase anchoring protein 10 A kinase anchor protein 10 isoform 3 A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10) A kinase anchor protein 10 isoform 5 |
Synonyms | |
Description | FUNCTION: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity). . |
Accessions | ENST00000572341.5 ENST00000225737.11 J3QRM7 A0A0S2Z4Z7 ENST00000571858.1 A0A0S2Z5A1 ENST00000583951.1 I3L479 A0A0S2Z551 ENST00000576896.5 ENST00000578898.1 ENST00000460046.2 I3L177 K7EM25 J3QL61 J3QR74 ENST00000582611.5 E7EMD6 ENST00000395536.7 A0A0S2Z4Y8 A0A0S2Z513 O43572 I3NI04 |