AASDHPPT report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015939Biological processpantothenate metabolic process
GO_0019878Biological processlysine biosynthetic process via aminoadipic acid
GO_0009258Biological process10-formyltetrahydrofolate catabolic process
GO_0051604Biological processprotein maturation
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0005515Molecular functionprotein binding
GO_0008897Molecular functionholo-[acyl-carrier-protein] synthase activity
GO_0000287Molecular functionmagnesium ion binding

IV. Literature review

[source]
Gene nameAASDHPPT
Protein nameL-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (EC 2.7.8.7) (4'-phosphopantetheinyl transferase) (Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase)
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (EC 2.7.8.7) (4'-phosphopantetheinyl transferase) (Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase) (AASD-PPT) (LYS5 ortholog)
SynonymsHSPC223
x0005
CGI-80
HAH-P
DescriptionFUNCTION: Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A, regardless of whether the CoA is presented in the free thiol form or as an acetyl thioester, to a serine residue of a broad range of acceptors including the acyl carrier domain of FASN. .

AccessionsE9PNF3
ENST00000524411.5
Q9NRN7
ENST00000525660.1 [Q9NRN7-2]
ENST00000533423.5
ENST00000278618.9 [Q9NRN7-1]
E9PLW6