Interactors | Protein name | Directionality | Classification | |
|---|---|---|---|---|
| 1 | WNT3A-FZD10+LRP5 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 2 | WNT3A-FZD10+LRP6 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 3 | WNT3A-FZD1+LRP5 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 4 | WNT3A-FZD1+LRP6 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 5 | WNT3A-FZD2+LRP5 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 6 | WNT3A-FZD2+LRP6 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 7 | WNT3A-FZD3+LRP5 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 8 | WNT3A-FZD3+LRP6 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 9 | WNT3A-FZD4+LRP5 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 10 | WNT3A-FZD4+LRP6 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 11 | WNT3A-FZD5+LRP5 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 12 | WNT3A-FZD5+LRP6 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 13 | WNT3A-FZD6+LRP5 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 14 | WNT3A-FZD6+LRP6 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 15 | WNT3A-FZD7+LRP5 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 16 | WNT3A-FZD7+LRP6 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 17 | WNT3A-FZD8+LRP5 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 18 | WNT3A-FZD8+LRP6 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 19 | WNT3A-FZD8+RYK | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 20 | WNT3A-FZD9+LRP5 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| 21 | WNT3A-FZD9+LRP6 | WNT3A_HUMAN - | Ligand-Receptor | Signaling by WNT |
| Name | Wnt-Frizzled-LRP5/6 complex |
| ID | GO_1990851 |
| collection_id | Cellular component |
| Exact synonym | Wnt-FZD-LRP5/6 trimeric complex, Wnt.Fz.LRP ternary complex |
| Description | A protein complex containing a secreted Wnt protein associated with its receptor, Frizzled (Fz), and co-receptor low density lipoprotein receptor-related protein 5 (LRP5) or LRP6. |
| Related synonym | Frizzled-LRP5/6 complex, Wnt-induced Frizzled-LRP5/6 complex |
| Comment | Given the number of Wnt proteins, Frizzled proteins and LRP proteins, many different trimeric complexes are likely to form. |
| External URL | |
| Genes |