| Name | hypoxia-inducible factor-1alpha signaling pathway |
| ID | GO_0097411 |
| collection_id | Biological process |
| Exact synonym | HIF1alpha pathway, hypoxia-inducible factor signaling, hypoxia-inducible factor-1alpha signalling pathway |
| Description | The series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia. |
| External URL | |
| Genes |