LUBAC complex

I. Literature review

[source]
NameLUBAC complex
IDGO_0071797
collection_id

Cellular component

Description

A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex.

External URL
Genes