Name | BRCA1-C complex |
ID | GO_0070533 |
collection_id | Cellular component |
Description | A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint. |
External URL | |
Genes |