BRCA1-C complex

I. Literature review

[source]
NameBRCA1-C complex
IDGO_0070533
collection_id

Cellular component

Description

A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint.

External URL
Genes