| Name | MDA-5 signaling pathway |
| ID | GO_0039530 |
| collection_id | Biological process |
| Exact synonym | IFIH1 signaling pathway, MDA-5 signalling pathway, melanoma differentiation-associated gene 5 signaling pathway |
| Description | The series of molecular signals initiated by the binding of dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1). MDA-5 detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines. |
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