Mre11 complex

I. Literature review

[source]
NameMre11 complex
IDGO_0030870
collection_id

Cellular component

Exact synonym

MRN complex, MRX complex, RAD50-MRE11-NBN complex, RMX complex, Rad50 complex, Rad50-Rad32-Nbs1 complex

Description

Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins.

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Genes