Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 11 studies | 31% ± 12% | |
| epithelial cell | 5 studies | 27% ± 8% | |
| endothelial cell | 3 studies | 22% ± 3% | |
| fibroblast | 3 studies | 24% ± 8% | |
| glutamatergic neuron | 3 studies | 39% ± 14% | |
| interneuron | 3 studies | 37% ± 18% | |
| neuron | 3 studies | 24% ± 5% | |
| oligodendrocyte | 3 studies | 19% ± 1% | |
| astrocyte | 3 studies | 24% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 27% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 5657.23 | 653 / 653 | 97% | 7.93 | 588 / 605 |
| prostate | 100% | 4212.78 | 245 / 245 | 97% | 5.57 | 486 / 502 |
| brain | 97% | 2821.24 | 2558 / 2642 | 100% | 9.17 | 704 / 705 |
| adrenal gland | 100% | 3233.69 | 258 / 258 | 96% | 7.36 | 221 / 230 |
| pancreas | 100% | 2106.77 | 328 / 328 | 96% | 5.92 | 171 / 178 |
| ovary | 100% | 5247.75 | 180 / 180 | 94% | 6.42 | 403 / 430 |
| esophagus | 100% | 2597.26 | 1441 / 1445 | 93% | 5.41 | 171 / 183 |
| intestine | 100% | 3456.84 | 966 / 966 | 92% | 4.74 | 487 / 527 |
| breast | 100% | 3412.44 | 459 / 459 | 92% | 5.70 | 1033 / 1118 |
| kidney | 100% | 3233.92 | 89 / 89 | 91% | 7.34 | 823 / 901 |
| stomach | 100% | 2530.39 | 359 / 359 | 89% | 4.13 | 254 / 286 |
| uterus | 100% | 4577.56 | 170 / 170 | 87% | 4.79 | 401 / 459 |
| bladder | 100% | 4056.33 | 21 / 21 | 87% | 4.54 | 438 / 504 |
| lung | 100% | 3411.62 | 578 / 578 | 86% | 4.98 | 998 / 1155 |
| skin | 100% | 2259.77 | 1808 / 1809 | 83% | 4.45 | 391 / 472 |
| liver | 100% | 2012.81 | 225 / 226 | 70% | 3.30 | 283 / 406 |
| adipose | 100% | 2895.02 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4879.57 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3028.20 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 96% | 1485.39 | 824 / 861 | 0% | 0 | 0 / 0 |
| muscle | 94% | 1278.09 | 753 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 5.16 | 24 / 29 |
| eye | 0% | 0 | 0 / 0 | 76% | 4.00 | 61 / 80 |
| peripheral blood | 73% | 1213.97 | 674 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 67% | 2.69 | 30 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007095 | Biological process | mitotic G2 DNA damage checkpoint signaling |
| GO_0006974 | Biological process | DNA damage response |
| GO_0071168 | Biological process | protein localization to chromatin |
| GO_2001032 | Biological process | regulation of double-strand break repair via nonhomologous end joining |
| GO_0006281 | Biological process | DNA repair |
| GO_1905168 | Biological process | positive regulation of double-strand break repair via homologous recombination |
| GO_0010212 | Biological process | response to ionizing radiation |
| GO_0045860 | Biological process | positive regulation of protein kinase activity |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0030870 | Cellular component | Mre11 complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| GO_0003682 | Molecular function | chromatin binding |
| Gene name | MRNIP |
| Protein name | MRN complex interacting protein MRN complex-interacting protein (MRN-interacting protein) MRN complex interacting protein (cDNA FLJ56341) |
| Synonyms | C5orf45 |
| Description | FUNCTION: Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex . Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair . |
| Accessions | ENST00000376931.6 [Q6NTE8-3] ENST00000640658.1 [Q6NTE8-3] E5RK98 ENST00000523737.5 B7Z1T6 F6XPR0 ENST00000518219.5 ENST00000518235.5 ENST00000521333.5 ENST00000520995.5 ENST00000519213.1 ENST00000524068.5 ENST00000519208.5 Q6NTE8 E7EMV9 ENST00000523084.5 ENST00000523835.5 ENST00000522157.5 E5RIC8 ENST00000522663.5 E5RI52 ENST00000292586.11 [Q6NTE8-1] E5RIJ7 E5RGF8 ENST00000520698.5 E5RJC6 E5RHY8 E5RHV0 ENST00000521299.5 F6UWW1 ENST00000639632.2 [Q6NTE8-1] |
