ZPR1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0031641Biological processregulation of myelination
GO_0045927Biological processpositive regulation of growth
GO_0061564Biological processaxon development
GO_0006397Biological processmRNA processing
GO_0021510Biological processspinal cord development
GO_0033120Biological processpositive regulation of RNA splicing
GO_0071364Biological processcellular response to epidermal growth factor stimulus
GO_0007165Biological processsignal transduction
GO_0001833Biological processinner cell mass cell proliferation
GO_0010628Biological processpositive regulation of gene expression
GO_1990261Biological processpre-mRNA catabolic process
GO_0042307Biological processpositive regulation of protein import into nucleus
GO_0030576Biological processCajal body organization
GO_0006260Biological processDNA replication
GO_0006457Biological processprotein folding
GO_0008380Biological processRNA splicing
GO_0000226Biological processmicrotubule cytoskeleton organization
GO_2000672Biological processnegative regulation of motor neuron apoptotic process
GO_0042023Biological processDNA endoreduplication
GO_0001834Biological processtrophectodermal cell proliferation
GO_1902742Biological processapoptotic process involved in development
GO_0045787Biological processpositive regulation of cell cycle
GO_0005730Cellular componentnucleolus
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0043204Cellular componentperikaryon
GO_0005654Cellular componentnucleoplasm
GO_0043025Cellular componentneuronal cell body
GO_0030426Cellular componentgrowth cone
GO_0005737Cellular componentcytoplasm
GO_0015030Cellular componentCajal body
GO_0097504Cellular componentGemini of coiled bodies
GO_0030424Cellular componentaxon
GO_0005634Cellular componentnucleus
GO_0031369Molecular functiontranslation initiation factor binding
GO_0044183Molecular functionprotein folding chaperone
GO_0008270Molecular functionzinc ion binding
GO_0005515Molecular functionprotein binding
GO_0030971Molecular functionreceptor tyrosine kinase binding

IV. Literature review

[source]
Gene nameZPR1
Protein nameZinc finger protein ZPR1 (Zinc finger protein 259)
ZPR1 zinc finger
SynonymsZNF259
DescriptionFUNCTION: Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus. It is involved in the positive regulation of cell cycle progression . Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies. Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons. Plays a role in the splicing of cellular pre-mRNAs. May be involved in H(2)O(2)-induced neuronal cell death. .

AccessionsF8WBC5
H7BZS1
ENST00000429220.5
H7BZM7
O75312
H7C449
ENST00000425791.1
ENST00000449430.1
ENST00000444935.5
ENST00000227322.8
H7C0E5
ENST00000431973.5