ZNF354C report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ZNF354C at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZNF354C at tissue level.

III. Associated gene sets

GO_0001525Biological processangiogenesis
GO_1903671Biological processnegative regulation of sprouting angiogenesis
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0031965Cellular componentnuclear membrane
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameZNF354C
Protein nameZinc finger protein 354C (Kidney, ischemia, and developmentally-regulated protein 3) (hKID3)
SynonymsKID3
DescriptionFUNCTION: Transcriptional repressor that inhibits endothelial angiogenic sprouting . Suppresses osteogenic effects of RUNX2 and may be involved in osteoblastic differentiation (By similarity). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity). .

AccessionsQ86Y25
ENST00000315475.7