I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 22% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 22% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 917.10 | 1445 / 1445 | 99% | 7.11 | 182 / 183 |
| breast | 100% | 1524.15 | 459 / 459 | 98% | 7.74 | 1101 / 1118 |
| uterus | 100% | 1348.88 | 170 / 170 | 98% | 7.38 | 450 / 459 |
| prostate | 100% | 1320.91 | 245 / 245 | 98% | 6.82 | 491 / 502 |
| thymus | 100% | 1482.94 | 653 / 653 | 97% | 7.45 | 588 / 605 |
| pancreas | 100% | 683.93 | 328 / 328 | 96% | 6.10 | 171 / 178 |
| brain | 97% | 543.31 | 2553 / 2642 | 99% | 7.37 | 700 / 705 |
| bladder | 100% | 1045.29 | 21 / 21 | 95% | 5.70 | 480 / 504 |
| lung | 100% | 940.41 | 578 / 578 | 95% | 6.03 | 1100 / 1155 |
| ovary | 100% | 1117.12 | 180 / 180 | 95% | 5.56 | 407 / 430 |
| kidney | 100% | 887.84 | 89 / 89 | 93% | 7.61 | 839 / 901 |
| adrenal gland | 100% | 723.19 | 258 / 258 | 93% | 4.63 | 213 / 230 |
| intestine | 100% | 1054.23 | 966 / 966 | 93% | 5.13 | 488 / 527 |
| stomach | 100% | 770.92 | 359 / 359 | 92% | 5.14 | 263 / 286 |
| skin | 100% | 775.12 | 1809 / 1809 | 79% | 4.83 | 372 / 472 |
| liver | 98% | 384.38 | 222 / 226 | 67% | 2.83 | 272 / 406 |
| adipose | 100% | 1359.95 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 875.85 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1133.47 | 241 / 241 | 0% | 0 | 0 / 0 |
| muscle | 98% | 366.34 | 785 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 447.81 | 839 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 5.64 | 42 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 62% | 3.26 | 18 / 29 |
| eye | 0% | 0 | 0 / 0 | 48% | 2.54 | 38 / 80 |
| peripheral blood | 37% | 203.33 | 342 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0003714 | Molecular function | transcription corepressor activity |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0003682 | Molecular function | chromatin binding |
| Gene name | ZNF354B |
| Protein name | Zinc finger protein 354B |
| Synonyms | |
| Description | FUNCTION: Transcriptional repressor that binds DNA upon activation by RAS proteins signal transduction to initiate transcriptional silencing through the recruitment of additional DNA-binding proteins, multisubunit complexes and chromatin-modifying activities to establish a platform for DNMT1 recruitment. . |
| Accessions | E5RH89 ENST00000520377.1 A0A1S5UZ15 Q96LW1 ENST00000322434.8 |
